γ-Secretase Inhibitor I CAS 133407-83-7
| CAS No. | 133407-83-7 |
| Molecular Formula | C26H41N3O5 |
| Molecular Weight | 475.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of γ-Secretase Inhibitor I is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
γ-Secretase Inhibitor I (CAS 133407-83-7) is a high-purity analytical reference standard with the molecular formula C26H41N3O5 and a molecular weight of 475.62 g/mol.
γ-Secretase Inhibitor I (C26H41N3O5) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H41N3O5 |
| Molecular Weight | 475.62 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Nitrogen Atoms | 3 |
Related Secretase Standards
Recommended Standards
- MG 132 (CAS 133407-82-6)
- 2-(4-(Methylsulfonyl)phenyl)-5-(2-(pyrrolidin-1-yl)pyridin-4-yl)-4-(m-tolyl)thiazole (CAS 365429-51-2)
- Rimegepant Impurity 104 (CAS 1356400-55-9)
- 5-((3-(4-(Allyloxy)phenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-3-(sec-butyl)-2-thioxothiazolidin-4-one (CAS 623933-03-9)
- 3-(3-Cyano-4-methylphenyl)-1-(4-ethoxyphenyl)thiourea (CAS 301193-68-0)
- 1-(4-Fluorophenyl)-5-oxopyrrolidine-3-carbonitrile (CAS 1017458-39-7)
- Thiophene-2-carboxylic anhydride (CAS 25569-97-5)
- 5-(Hydroxymethyl)-1-methylpiperidin-2-one (CAS 1780429-54-0)
- Olprinone Impurity 9 (CAS 913835-63-9)
- β-Bungarotoxin (CAS 12778-32-4)
- 7-(Chloromethyl)-2-methylbenzo[b]thiophene (CAS 1234845-02-3)
- Methyl 5-ethyl-3-methylbenzofuran-2-carboxylate (CAS 1269531-94-3)
- [6-Methoxy-2-(4-methoxyphenyl)benzo[b]furan-3-yl](4-cyanophenyl)methanone (CAS 176977-56-3)
- Des-Pro31-Tirzepatide (CAS CATO-CPTD788943)
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