2-(4-(Methylsulfonyl)phenyl)-5-(2-(pyrrolidin-1-yl)pyridin-4-yl)-4-(m-tolyl)thiazole CAS 365429-51-2
| CAS No. | 365429-51-2 |
| Molecular Formula | C26H25N3O2S2 |
| Molecular Weight | 475.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 475.63 g/mol gives 2-(4-(Methylsulfonyl)phenyl)-5-(2-(pyrrolidin-1-yl)pyridin-4-yl)-4-(m-tolyl)thiazole distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(4-(Methylsulfonyl)phenyl)-5-(2-(pyrrolidin-1-yl)pyridin-4-yl)-4-(m-tolyl)thiazole (CAS 365429-51-2), molecular formula C26H25N3O2S2 and molecular weight 475.63 g/mol, is a CATO reference standard with documented purity and traceability.
2-(4-(Methylsulfonyl)phenyl)-5-(2-(pyrrolidin-1-yl)pyridin-4-yl)-4-(m-tolyl)thiazole (C26H25N3O2S2) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H25N3O2S2 |
| Molecular Weight | 475.63 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related Methylsulfonyl Standards
- 4-Methylsulfonyl-2,2',3',4',5,5',6-heptachlorobiphenyl (CAS 153310-30-6)
- N-(Methylsulfonyl)-N-(4-((3-nitroacridin-9-yl)amino)phenyl)butyramide (CAS 61068-06-2)
- N2-(Methylsulfonyl)-N2-trityl-L-glutamine (CAS 2230674-05-0)
- 2-(Methylsulfonyl)-5-(tributylstannyl)thiazole (CAS 1245816-12-9)
- 2-(methylsulfonyl)-4-(tributylstannyl)thiazole (CAS 1245816-14-1)
- N-(Methylsulfonyl)-N-(4-((3-nitroacridin-9-yl)amino)phenyl)acetamide (CAS 61068-04-0)
- 5-(3-(Methylsulfonyl)phenyl)-N-(6-(piperidin-4-yl)pyridin-3-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine (CAS 1202490-36-5)
- 2-(Methylsulfonyl)-5-(tributylstannyl)pyrimidine (CAS 122476-85-1)
Recommended Standards
- γ-Secretase Inhibitor I (CAS 133407-83-7)
- 5-((3-(4-(Allyloxy)phenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-3-(sec-butyl)-2-thioxothiazolidin-4-one (CAS 623933-03-9)
- MG 132 (CAS 133407-82-6)
- N-([1,1'-Biphenyl]-2-yl)-2-((3-ethyl-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 577789-79-8)
- (2E)-3-(3-chloro-4,5-dimethoxyphenyl)acrylic acid (CAS 736948-93-9)
- 2-Methoxydibenzo[b,d]furan (CAS 20357-70-4)
- (3S)-1-(Pyrimidin-4-yl)pyrrolidin-3-amine hydrochloride (CAS 1365936-46-4)
- 2-(Benzhydryloxy)-N,N,N-triethylethan-1-aminium bromide (CAS 102571-29-9)
- 2-(4-(Difluoromethoxy)phenyl)-2-hydroxyacetic acid (CAS 1214377-14-6)
- 6027-02-7 HISTIDINE,(L) Histidine dihydrochloride Histidine, L- L-Histidine dihydrochloride L-Histidine, dihydrochloride NSC-27422 NSC27422 (CAS 6027-02-7)
- [(Benzo[1,3]dioxole-5-carbonyl)-amino]-acetic acid ethyl ester (CAS 76208-96-3)
- 7-Hydroxyquinoline-6-carboxylic acid (CAS 1227608-04-9)
- 2-(Benzylamino)-1-(pyrrolidin-1-yl)ethanethione (CAS 777946-67-5)
- Semaglutide Impurity 148 (CAS CATO-C4X-2226148)
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