3-Methyl-6-[3-(trifluoromethyl)phenyl]-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid CAS 1334149-52-8
| CAS No. | 1334149-52-8 |
| Molecular Formula | C15H9F3N2O3 |
| Molecular Weight | 322.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 322.24 g/mol gives 3-Methyl-6-[3-(trifluoromethyl)phenyl]-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-Methyl-6-[3-(trifluoromethyl)phenyl]-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 1334149-52-8) is a high-purity analytical reference standard with the molecular formula C15H9F3N2O3 and a molecular weight of 322.24 g/mol.
The molecular framework of 3-Methyl-6-[3-(trifluoromethyl)phenyl]-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid (C15H9F3N2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H9F3N2O3 |
| Molecular Weight | 322.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Methyl Standards
- 2-(5-Oxo-3-(trifluoromethyl)-2,5-dihydro-1H-pyrazol-1-yl)-6-phenylpyrimidin-4(3H)-one (CAS 900015-70-5)
- 3-Methyl-6-[2-(trifluoromethyl)phenyl]-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 924383-70-0)
- N-[3-(Trifluoromethyl)-2-quinoxalinyl]-2-furohydrazide (CAS 343372-43-0)
- 3,5-Bis[(trifluoromethyl)sulfanyl]benzoic acid (CAS 102117-40-8)
- 3,5-Bis(trifluoromethyl)benzyl methanesulphonate (CAS 183551-51-1)
- 3,5-Bis(trifluoromethyl)phenylsulfonylethanol (CAS 450409-87-7)
- Bis(4-(trifluoromethyl)phenyl)sulfane (CAS 90141-51-8)
- (5-(Trifluoromethyl)-2-(2-(trifluoromethyl)pyrimidin-5-yl)pyridin-4-yl)methanamine (CAS 1984827-95-3)
Recommended Standards
- Tert-butyl3-(5-bromopentoxy)azetidine-1-carboxylate (CAS 1221715-90-7)
- 5-(4-Cyanophenyl)-6-(2,2,2-trifluoroethoxy)nicotinic acid (CAS 1364678-39-6)
- 6-Hydroxy Bromantane (CAS 1007310-57-7)
- (E)-2-(2-(5-bromothiophen-2-yl)vinyl)benzo[d]thiazole (CAS 338401-69-7)
- 1-(1H-Imidazo[4,5-c]pyridin-4-yl)ethanone (CAS 146874-38-6)
- 6-Methoxy-2-methylnicotinamide (CAS 1824114-08-0)
- 5181-75-9 AR-1J6137 methyl prop-2-en-1-yl 4-(2-fluorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate (CAS 5181-75-9)
- (2-Cyclopropoxy-5-isopropoxyphenyl)methanamine (CAS 1243453-45-3)
- 1-(3-Bromo-4-methoxyphenyl)-N-methylmethanamine hydrochloride (CAS 855272-08-1)
- 3,4-Dichloro-2-iodotoluene (CAS 1803809-48-4)
- Dimethyl 1-(p-tolyl)-1H-1,2,3-triazole-4,5-dicarboxylate (CAS 166031-15-8)
- 6-Bromo-3-hydroxy-2,3-dihydro-1h-indol-2-one (CAS 1021021-75-9)
- 2-(2-Morpholino-2-oxoethoxy)benzaldehyde (CAS 125418-84-0)
- Insulin Degludec Impurity 10 (CAS CATO-C4X-215710)
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