5-(4-Cyanophenyl)-6-(2,2,2-trifluoroethoxy)nicotinic acid CAS 1364678-39-6
| CAS No. | 1364678-39-6 |
| Molecular Formula | C15H9F3N2O3 |
| Molecular Weight | 322.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 5-(4-Cyanophenyl)-6-(2,2,2-trifluoroethoxy)nicotinic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
5-(4-Cyanophenyl)-6-(2,2,2-trifluoroethoxy)nicotinic acid (CAS 1364678-39-6) is a high-purity analytical reference standard with the molecular formula C15H9F3N2O3 and a molecular weight of 322.24 g/mol.
Structurally, 5-(4-Cyanophenyl)-6-(2,2,2-trifluoroethoxy)nicotinic acid (C15H9F3N2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 322.24 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C15H9F3N2O3 |
| Molecular Weight | 322.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Cyanophenyl Standards
- 4-Cyanophenyl 4-heptylbenzoate (CAS 38690-76-5)
- N-(2-Cyanophenyl)-2-[4-(pyridin-2-yl)piperazin-1-yl]acetamide (CAS 329779-50-2)
- N-(2-Cyanophenyl)-2-(2,4-dichlorophenoxy)acetamide (CAS 306316-35-8)
- N-(4-(4-Cyanophenyl)thiazol-2-yl)-3-fluorobenzamide (CAS 476283-16-6)
- 3-[(3-Cyanophenyl)methoxy]pyrido[1,2-a]indole-10-carbonitrile (CAS 338981-95-6)
- 2-[1-(2-Cyanophenyl)-1H-pyrrol-2-yl]-2-oxo-N,N-bis(propan-2-yl)acetamide (CAS 866010-85-7)
- N-(4-cyanophenyl)-4-(pyridin-2-yl)piperazine-1-carbothioamide (CAS 497060-96-5)
- 4-Cyanophenyl 2-(1,3-dioxo-2,3-dihydro-1h-isoindol-2-yl)propanoate (CAS 727980-91-8)
Recommended Standards
- 3-Methyl-6-[3-(trifluoromethyl)phenyl]-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 1334149-52-8)
- (E)-2-(2-(5-bromothiophen-2-yl)vinyl)benzo[d]thiazole (CAS 338401-69-7)
- Tert-butyl3-(5-bromopentoxy)azetidine-1-carboxylate (CAS 1221715-90-7)
- [S(S)]-N-[(1S)-1-(4-Bromo-3-fluorophenyl)ethyl]-2-methyl-2-propanesulfinamide (CAS 2813339-48-7)
- 4-(Difluoromethyl)-5-methoxy-3-nitropyridin-2-ol (CAS 1805446-87-0)
- N-(5-nitropyridin-2-yl)cyclopropanecarboxamide (CAS 26207-88-5)
- 4-(Acetyloxy)-5-[[2-(acetyloxy)-5-(2-bromo-1-hydroxyethyl)phenyl]methyl]-α1-(bromomethyl)-1,3-benzenedimethanol α3-Acetate (CAS 438246-23-2)
- 69111-37-1 (~6~Li)Lithium nitrate DTXSID00745969 (CAS 69111-37-1)
- Fmoc-Asn(Dod)-OH (CAS 113534-16-0)
- Methyl (2Z)-2-(4-chlorobenzenesulfonyl)-3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]prop-2-enoate (CAS 1327187-59-6)
- Methy 3-iodo-1H-indole-2-carboxylate (CAS 534595-85-2)
- 3-(2-Methoxyphenyl)-4-methyl-1H-pyrazol-5-amine hydrochloride (CAS 1106569-46-3)
- Apremilast Impurity 113 (CAS CATO-C4X-1009113)
- Semaglutide impurity 244(Fmoc-His(Fmoc)-Aib-OH) (CAS CATO-C4X-2226244)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com