8-Chloro-3-iodo-2-methylimidazo[1,2-a]pyrazine CAS 1334167-35-9
| CAS No. | 1334167-35-9 |
| Molecular Formula | C7H5ClIN3 |
| Molecular Weight | 293.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 293.49 g/mol gives 8-Chloro-3-iodo-2-methylimidazo[1,2-a]pyrazine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
8-Chloro-3-iodo-2-methylimidazo[1,2-a]pyrazine (CAS 1334167-35-9), molecular formula C7H5ClIN3 and molecular weight 293.49 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 8-Chloro-3-iodo-2-methylimidazo[1,2-a]pyrazine (C7H5ClIN3) contains a nitrile group, chlorine/iodine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 293.49 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H5ClIN3 |
| Molecular Weight | 293.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 6-chloro-3-iodo-1H-indazol-5-amine (CAS 1000342-50-6)
- 4-Chloro-3-iodo-1H-indazol-7-amine (CAS 1000343-04-3)
- 5-chloro-4-iodo-2-methoxybenzonitrile (CAS 1057339-09-9)
- 4-Chloro-5-iodo-2-methyl-7H-pyrrolo[2,3-d]pyrimidine, 97% (CAS 1060815-92-0)
- (3-((3-Chloro-4-fluorophenyl)carbamoyl)phenyl)boronic acid (CAS 1072946-04-3)
- 2-Chloro-7-iodo-5-methyl-5H-pyrrolo[3,2-d]pyrimidine, 97% (CAS 1152475-62-1)
- 6-Chloro-3-iodo-2-methylimidazo[1,2-b]pyridazine (CAS 1208069-55-9)
- 4-Chloro-5-iodo-6-methyl-7H-pyrrolo[2,3-d]pyrimidine (CAS 1229936-44-0)
Recommended Standards
- 6-Chloro-8-iodo-2-methylimidazo[1,2-b]pyridazine (CAS 1298031-96-5)
- 4-Chloro-3-iodo-6-methyl-1H-pyrazolo[4,3-c]pyridine (CAS 1347759-25-4)
- 5-Chloro-6-iodoisoindolin-1-one (CAS 1262416-25-0)
- 4-Chloro-6-iodo-7-methyl-7H-pyrrolo[2,3-d]pyrimidine (CAS 1363382-83-5)
- (11bR)-4-Hydroxy-2,6-diphenyl-8,9,10,11,12,13,14,15-octahydrodinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepine 4-Oxide (CAS 791616-65-4)
- 1-((2-Nitrophenyl)sulfonyl)-4-(pyridin-2-yl)piperazine (CAS 309277-86-9)
- 2-chloro-5-[5-(3-chlorophenyl)-1,3-oxazol-2-yl]-4-(trifluoromethyl)pyridine (CAS 680213-96-1)
- 4-Amino-N-cyclohexyl-1-ethyl-1H-pyrazole-5-carboxamide (CAS 1494516-36-7)
- Ethyl 2,2-dichloro-2-fluoroacetate (CAS 383-61-9)
- 5-Methyl-3-[4-(trifluoromethyl)phenyl]-1,2,4-oxadiazole (CAS 1823492-16-5)
- 3-(3-Bromophenyl)-1-(2,4-dimethylphenyl)propan-1-one (CAS 898760-21-9)
- 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]thiazole (CAS 1002309-47-8)
- 1-Chloro-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinoline (CAS 1313761-15-7)
- Insulin Degludec Impurity 28 (CAS CATO-C4X-215728)
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