4-Chloro-6-iodo-7-methyl-7H-pyrrolo[2,3-d]pyrimidine CAS 1363382-83-5
| CAS No. | 1363382-83-5 |
| Molecular Formula | C7H5ClIN3 |
| Molecular Weight | 293.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Chloro-6-iodo-7-methyl-7H-pyrrolo[2,3-d]pyrimidine is closely related to a nitrile group, chlorine/iodine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-Chloro-6-iodo-7-methyl-7H-pyrrolo[2,3-d]pyrimidine (CAS 1363382-83-5), molecular formula C7H5ClIN3 and molecular weight 293.49 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Chloro-6-iodo-7-methyl-7H-pyrrolo[2,3-d]pyrimidine (C7H5ClIN3) is characterized by a nitrile group, chlorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Chloro-6-iodo-7-methyl-7H-pyrrolo[2,3-d]pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5ClIN3 |
| Molecular Weight | 293.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 6-chloro-3-iodo-1H-indazol-5-amine (CAS 1000342-50-6)
- 4-Chloro-3-iodo-1H-indazol-7-amine (CAS 1000343-04-3)
- 5-chloro-4-iodo-2-methoxybenzonitrile (CAS 1057339-09-9)
- 4-Chloro-5-iodo-2-methyl-7H-pyrrolo[2,3-d]pyrimidine, 97% (CAS 1060815-92-0)
- (3-((3-Chloro-4-fluorophenyl)carbamoyl)phenyl)boronic acid (CAS 1072946-04-3)
- 2-Chloro-7-iodo-5-methyl-5H-pyrrolo[3,2-d]pyrimidine, 97% (CAS 1152475-62-1)
- 6-Chloro-3-iodo-2-methylimidazo[1,2-b]pyridazine (CAS 1208069-55-9)
- 4-Chloro-5-iodo-6-methyl-7H-pyrrolo[2,3-d]pyrimidine (CAS 1229936-44-0)
Recommended Standards
- 4-Chloro-3-iodo-6-methyl-1H-pyrazolo[4,3-c]pyridine (CAS 1347759-25-4)
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- 8-Chloro-3-iodo-2-methylimidazo[1,2-a]pyrazine (CAS 1334167-35-9)
- 2-Chloro-5-iodo-1H-benzo[d]imidazol-6-amine (CAS 142356-55-6)
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