3-[3-Fluoro-5-(methoxycarbonyl)phenyl]phenylacetic acid CAS 1334500-13-8
| CAS No. | 1334500-13-8 |
| Molecular Formula | C16H13FO4 |
| Molecular Weight | 288.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3-[3-Fluoro-5-(methoxycarbonyl)phenyl]phenylacetic acid (CAS 1334500-13-8), a certified reference material (molecular formula C16H13FO4, MW 288.27 g/mol) for analytical method development and quality control.
The molecular framework of 3-[3-Fluoro-5-(methoxycarbonyl)phenyl]phenylacetic acid (C16H13FO4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H13FO4 |
| Molecular Weight | 288.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
Related Fluoro Standards
- Methyl 3-fluoro-4-[4-(methoxycarbonyl)phenyl]benzoate (CAS 1155408-24-4)
- Methyl 2-fluoro-4-[2-(methoxycarbonyl)phenyl]benzoate (CAS 1820603-43-7)
- Methyl 2-fluoro-4-[3-(methoxycarbonyl)phenyl]benzoate (CAS 1820603-48-2)
- Methyl 5-fluoro-2-[2-(methoxycarbonyl)phenyl]benzoate (CAS 1820674-38-1)
- Methyl 2-fluoro-5-[4-(methoxycarbonyl)phenyl]benzoate (CAS 1820706-97-5)
- Methyl 2-fluoro-5-[3-(methoxycarbonyl)phenyl]benzoate (CAS 1820740-46-2)
- 4-(2-Fluoro-4-nitrophenoxy)-5-methyl-5H-pyrrolo[3,2-d]pyrimidine (CAS 875339-19-8)
- 4-(3-Fluoro-4-nitrophenoxy)-5-methyl-5H-pyrrolo[3,2-d]pyrimidine (CAS 919278-19-6)
Recommended Standards
- Benzyl 3-(trifluoromethyl)piperazine-1-carboxylate (CAS 1279815-93-8)
- Dimethyl 2-fluorobiphenyl-3,3'-dicarboxylate (CAS 1381944-85-9)
- Methyl 2-((1,6-dihydro-7H-pyrrolo[2,3-b]pyridin-7-yl)oxy)-4-fluorobenzoate (CAS 1235865-75-6)
- 2-[[2-[(4-Fluorophenyl)amino]-2-oxoethyl]amino]-benzoic acid (CAS 1394021-66-9)
- 5-(Benzyloxy)-2-(methylthio)pyrimidine (CAS 4874-32-2)
- (1r)-2,2,2-Trifluoro-1-(3-fluorophenyl)ethan-1-ol (CAS 1135312-06-9)
- (3-Aminophenyl)(azetidin-1-yl)methanone (CAS 1401253-65-3)
- (1R)-2-Bromo-1-(naphthalen-2-yl)ethan-1-ol (CAS 85554-14-9)
- 5-(hydroxymethyl)-5-phenylpiperidin-2-one (CAS 1909308-61-7)
- 2-Methyl-2-(4-(thiophen-2-yl)-1H-1,2,3-triazol-1-yl)propanoic acid (CAS 2138036-14-1)
- 2-(1,2,3-Thiadiazol-4-yl)phenyl 4-methoxybenzoate (CAS 303148-82-5)
- 4-Bromo-5-chloro-6-methylnicotinic acid (CAS 1423025-36-8)
- 2-{[4-(1-Methyl-1-phenylethyl)-phenoxy]methyl}oxirane (CAS 61578-04-9)
- Neuropeptide Y (porcine) trifluoroacetate salt (CAS 83589-17-7)
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