Methyl 2-fluoro-4-[2-(methoxycarbonyl)phenyl]benzoate CAS 1820603-43-7
| CAS No. | 1820603-43-7 |
| Molecular Formula | C16H13FO4 |
| Molecular Weight | 288.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Methyl 2-fluoro-4-[2-(methoxycarbonyl)phenyl]benzoate (CAS 1820603-43-7) is a high-purity analytical reference standard with the molecular formula C16H13FO4 and a molecular weight of 288.27 g/mol.
The molecular framework of Methyl 2-fluoro-4-[2-(methoxycarbonyl)phenyl]benzoate (C16H13FO4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H13FO4 |
| Molecular Weight | 288.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
Related Methyl Standards
- Methyl 3-fluoro-4-[4-(methoxycarbonyl)phenyl]benzoate (CAS 1155408-24-4)
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- Methyl 2-fluoro-4-[3-(methoxycarbonyl)phenyl]benzoate (CAS 1820603-48-2)
- Methyl 5-fluoro-2-[2-(methoxycarbonyl)phenyl]benzoate (CAS 1820674-38-1)
- Methyl 2-fluoro-5-[4-(methoxycarbonyl)phenyl]benzoate (CAS 1820706-97-5)
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Recommended Standards
- (E)-1-(5-(dimethylamino)-3-oxopent-4-en-2-yl)-5-(trifluoromethyl)pyridin-2(1H)-one (CAS 1644602-78-7)
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- 4-(4-Bromo-1H-pyrazol-1-yl)benzaldehyde (CAS 1174064-63-1)
- 2-Chloro-1-(3-methylisoxazol-4-yl)ethan-1-one (CAS 2006435-27-2)
- n-(2,6-Dichlorophenyl)-2-(methylamino)acetamide hydrochloride (CAS 1049761-34-3)
- 5-(Benzyloxy)-2-fluoroaniline (CAS 342042-82-4)
- Hippadine (CAS 52886-06-3)
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