Iloperidone Hydroxy Impurity CAS 133454-55-4
| CAS No. | 133454-55-4 |
| Molecular Formula | C24H29FN2O4 |
| Molecular Weight | 428.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 428.50 g/mol gives Iloperidone Hydroxy Impurity distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Iloperidone Hydroxy Impurity (CAS 133454-55-4) is a certified pharmaceutical impurity reference standard with the molecular formula C24H29FN2O4 and a molecular weight of 428.50 g/mol.
Structurally, Iloperidone Hydroxy Impurity (C24H29FN2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 428.50 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Iloperidone Hydroxy Impurity meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H29FN2O4 |
| Molecular Weight | 428.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Iloperidone Standards
- Iloperidone Metabolite P88 (R Isomer) (CAS 501373-87-1)
- Iloperidone Metabolite P88 (S Isomer) (CAS 501373-88-2)
- Iloperidone Metabolites P95 (CAS 475110-48-6)
- Iloperidone-d3 (CAS 1071168-82-5)
- Iloperidone Impurity N1 (CAS 133454-47-4)
- Iloperidone Impurity 4 (CAS 133455-04-6)
- Iloperidone N-Oxide (CAS 1375651-09-4)
- Iloperidone Impurity 9 (CAS CATO-C4X-16619)
Recommended Standards
- Paliperidone Impurity 117 (CAS CATO-C4X-1724117)
- Paliperidone Impurity 118 (CAS CATO-C4X-1724118)
- Fmoc-N-Me-Cys(Acm)-OH (CAS 481642-19-7)
- Paliperidone impurity 133 (CAS CATO-C4X-1724133)
- Cefoxitin Impurity 38 (CAS CATO-C4X-157838)
- Nintedanib Impurity 38 (CAS 58378-33-9)
- Pemigatinib Impurity 4 (CAS CATO-C4X-30244)
- 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride (CAS 41994-51-8)
- Potassium 5-pyridin-4-yl-1,3,4-oxadiazole-2-thiolate (CAS 1024183-19-4)
- 2-(Azetidin-3-yloxy)-1-(pyrrolidin-1-yl)propan-1-one (CAS 1342438-39-4)
- Sodium molybdate dihydrate (CAS 10102-40-6)
- 5-(Furan-3-yl)pyrimidine-2,4(1H,3H)-dione (CAS 127235-94-3)
- 3'-O-Methyladenosine (CAS 10300-22-8)
- Allo-D-Ile17-Tirzepatide (CAS CATO-CPTD788962)
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