1-Chloroisoquinoline-8-carboxylic acid CAS 1337879-52-3
| CAS No. | 1337879-52-3 |
| Molecular Formula | 2*C10H6ClNO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
1-Chloroisoquinoline-8-carboxylic acid (CAS 1337879-52-3), molecular formula C10H6ClNO2 and molecular weight 207.61 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 1-Chloroisoquinoline-8-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 207.61 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | 2*C10H6ClNO2 |
| Molecular Weight | 207.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloroisoquinoline Standards
- 1-Chloroisoquinoline-3-carboxylic acid (CAS 1049606-80-5)
- 1-Chloroisoquinoline-5-sulfonyl chloride hydrochloride (CAS 105627-81-4)
- 3-Chloroisoquinoline-5-sulfonyl chloride (CAS 1145868-94-5)
- 1-chloroisoquinoline-3-carboxamide (CAS 1152888-86-2)
- 3-Chloroisoquinoline-1-carboxylic acid (CAS 1179149-10-0)
- 6-Chloroisoquinoline-1-carboxylic acid (CAS 1179149-30-4)
- 4-Chloroisoquinoline-1-carboxylic acid (CAS 1179149-31-5)
- 5-Chloroisoquinoline-1-carboxylic acid (CAS 1179149-33-7)
Recommended Standards
- Tert-butyl 6-(1-cyanocyclobutyl)-3,4-dihydro-1,5-naphthyridine-1(2H)-carboxylate (CAS 2314394-16-4)
- 1-Isocyano-2-methoxy-2-methyl-propane (CAS 109434-22-2)
- 5-(3,5-Dichlorophenyl)nicotinaldehyde (CAS 887973-82-2)
- Istradefylline impurity 38 (CAS CATO-C4X-106138)
- 5-Fluorochroman-4-amine hydrochloride (CAS 2490709-40-3)
- 2,2-Diphenyl-4-(piperidin-1-yl)butanenitrile (CAS 5424-08-8)
- Vinyl-d3 Bromide (gas) (stabilized with hydroquinone) (CAS 4666-78-8)
- 1-(5-(M-tolyl)-1,3,4-oxadiazol-2-yl)ethan-1-amine hydrochloride (CAS 1417635-64-3)
- 2-{pyrrolo[2,1-f][1,2,4]triazin-7-yl}acetaldehyde (CAS 1556313-47-3)
- Semaglutide-d15 (CAS 910463-68-2(non-labelled))
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