2,2-Diphenyl-4-(piperidin-1-yl)butanenitrile CAS 5424-08-8
| CAS No. | 5424-08-8 |
| Molecular Formula | C21H24N2 |
| Molecular Weight | 304.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2,2-Diphenyl-4-(piperidin-1-yl)butanenitrile (CAS 5424-08-8), a certified reference material (molecular formula C21H24N2, MW 304.43 g/mol) for analytical method development and quality control.
The molecular framework of 2,2-Diphenyl-4-(piperidin-1-yl)butanenitrile (C21H24N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 2,2-Diphenyl-4-(piperidin-1-yl)butanenitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H24N2 |
| Molecular Weight | 304.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 2-((2-Methoxyethyl)thio)-9-methyl-5H-thiochromeno[4,3-d]pyrimidine (CAS 478246-92-3)
- 2-methoxy-4-(4-(1-methylpiperidin-4-yl)piperazin-1-yl)aniline (CAS 877676-39-6)
- 1-(4-(Tricyclo[4.3.1.13,8]undecane-1-carbonyl)piperazin-1-yl)ethan-1-one (CAS 881441-21-0)
- 2-Methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)aniline (CAS 761440-75-9)
- (5,7-Dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methanol (CAS 54535-00-1)
- EDDP perchlorate (CAS 31161-17-8)
- 5-Amino-6-iodopyrazine-2-carboxylic acid (CAS 1363381-34-3)
- 2-Benzyl-5-((4-methylbenzyl)oxy)-3,4-dihydroisoquinolin-1(2H)-one (CAS 850905-32-7)
- 3-Iodo-2,4-dimethyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine (CAS 2306275-13-6)
- 2-(Mercaptoamino)-1H-pyrrolo[2,3-d]pyrimidin-4(7H)-one (CAS 65062-58-0)
- 4-Chloro-6-ethyl-2-(pyridin-2-yl)pyrimidine (CAS 1153411-91-6)
- 3-Cyclopropoxy-6-iodopicolinamide (CAS 1243355-46-5)
- Abemaciclib Impurity 140 (CAS 2124229-65-6)
- Peptide 431 (CAS CATO-CPTD788431)
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