Silodosin impurity N1 CAS 1338365-54-0
| CAS No. | 1338365-54-0 |
| Molecular Formula | C22H25N3O2 |
| Molecular Weight | 363.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 363.45 g/mol gives Silodosin impurity N1 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Silodosin impurity N1 (CAS 1338365-54-0) is a certified pharmaceutical impurity reference standard with the molecular formula C22H25N3O2 and a molecular weight of 363.45 g/mol.
Structurally, Silodosin impurity N1 (C22H25N3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 363.45 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H25N3O2 |
| Molecular Weight | 363.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 3 |
Related Silodosin Standards
- Silodosin S-amine Isomer (CAS 1201180-97-3)
- Silodosin Impurity 22 (CAS 239463-72-0)
- Silodosin Keto Impurity (CAS 350797-57-8)
- Silodosin Impurity 30 (CAS 1639265-45-4)
- Silodosin Impurity 20 (CAS 1375180-28-1)
- Silodosin Impurity 7 (CAS 350797-56-7)
- Silodosin Impurity 11 (CAS 160969-03-9)
- Silodosin Impurity 15 (CAS 2052161-50-7)
Recommended Standards
- tert-Butyl 2-(3-fluorophenyl)-3-sulfanylidene-1,4,8-triazaspiro[4.5]dec-1-ene-8-carboxylate (CAS 1325303-52-3)
- tert-Butyl 2-(6-((tert-butoxycarbonyl)amino)pyridin-3-yl)pyrrolidine-1-carboxylate (CAS 1352501-30-4)
- Propanoic acid, 2,2-dimethyl-, 3-[(1R,2R)-2-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]cyclopropyl]-4-hydroxyphenyl esteR, rel- (CAS 1322699-95-5)
- 2-[1-Benzyl-3-(tert-butyl)-1H-1,2,4-triazol-5-yl]-3-phenylpropanoic acid (CAS 1353500-73-8)
- Crizotinib Impurity 44 (CAS CATO-C4X-102544)
- Telmisartan Impurity 17 (CAS 1352492-08-0)
- Mirabegron Impurity 6 (CAS 1684452-83-2)
- 4-Chloro-2-(5-chloro-2-fluorophenyl)-5-(prop-1-en-2-yl)pyridine (CAS 1801335-02-3)
- Posaconazole Impurity 10 (CAS 149809-43-8)
- 1-(2-(2-(3-Fluorophenyl)thiazol-4-yl)ethyl)-3-(thiophen-2-yl)urea (CAS 1210930-00-9)
- 1-[4-(Hydroxymethyl)piperidin-1-yl]-2,2-dimethylpropan-1-one (CAS 155535-54-9)
- 5-Bromo-2-hydroxy-3,4-dimethoxybenzaldehyde (CAS 28006-96-4)
- 4-Ethyl-1,2,3-thiadiazol-5-amine (CAS 78385-16-7)
- Peptide Impurity 12 (CAS CATO-CPTD788812)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com