Silodosin Impurity 15 CAS 2052161-50-7
| CAS No. | 2052161-50-7 |
| Molecular Formula | C22H24F3N3O3 |
| Molecular Weight | 435.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 435.44 g/mol gives Silodosin Impurity 15 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Silodosin Impurity 15 (CAS 2052161-50-7, C22H24F3N3O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Silodosin Impurity 15 (C22H24F3N3O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 435.44 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H24F3N3O3 |
| Molecular Weight | 435.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Silodosin Standards
- Silodosin Impurity 5 (CAS CATO-C4X-17545)
- Silodosin Depropanol Impurity1 (CAS 2052161-47-2)
- Silodosin Impurity 6 (CAS 2755910-23-5)
- Silodosin Impurity 11 (CAS 239463-74-2)
- Silodosin Impurity 7 (CAS 350797-56-7)
- Silodosin Impurity 9 (CAS 885340-13-6)
- Silodosin Impurity 1 (CAS 175870-21-0)
- Silodosin (CAS 160970-64-9)
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