3-Chloro-6,8-dimethoxyisoquinoline CAS 13388-76-6
| CAS No. | 13388-76-6 |
| Molecular Formula | C11H10ClNO2 |
| Molecular Weight | 223.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Chloro-6,8-dimethoxyisoquinoline is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-Chloro-6,8-dimethoxyisoquinoline (CAS 13388-76-6) is a high-purity analytical reference standard with the molecular formula C11H10ClNO2 and a molecular weight of 223.66 g/mol.
The molecular framework of 3-Chloro-6,8-dimethoxyisoquinoline (C11H10ClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H10ClNO2 |
| Molecular Weight | 223.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 6-Chloro-2-(3,5-dimethyl-1h-pyrazol-1-yl)pyrimidin-4-amine (CAS 1014720-95-6)
- 3-(6-Chloro-1H-indol-3-yl)propanoic acid (CAS 1018612-14-0)
- 2-Chloro-4-(2-oxopyrrolidin-1-yl)benzaldehyde (CAS 1024204-74-7)
- 4-Chloro-2-(3-ethyl-1,2,4-oxadiazol-5-yl)aniline (CAS 1040345-45-6)
- Ethyl 6-chloro-1H-indole-5-carboxylate (CAS 1057076-52-4)
- Ethyl 4-chloro-1H-indole-5-carboxylate (CAS 1057076-56-8)
- Methyl 7-chloro-2-methyl-1H-indole-3-carboxylate (CAS 1082470-30-1)
- Methyl 4-chloro-2-methyl-1H-indole-3-carboxylate (CAS 1082470-33-4)
Recommended Standards
- 4-(Chloromethyl)-1-(2-methoxyphenyl)-1h-1,2,3-triazole (CAS 1338689-28-3)
- 2-Chloro-6,8-dimethoxyquinoline (CAS 1339143-31-5)
- 4-[5-(Chloromethyl)-1h-1,2,3-triazol-1-yl]phenyl methyl ether (CAS 1338654-59-3)
- 2-chloro-4-(3-ethyl-1,2,4-oxadiazol-5-yl)aniline (CAS 1340316-99-5)
- Ethyl 3-Methoxy-4-oxopiperidine-1-carboxylate (CAS 83863-72-3)
- 3-Chloro-4,6-dihydroxy-2-methylbenzaldehyde (CAS 83324-59-8)
- 3-((4-Chloro-3-nitrophenyl)amino)-1-(4-fluorophenyl)propan-1-one (CAS 882748-61-0)
- (3-Chloro-5-cyclopropoxypyridin-2-yl)methanamine (CAS 1243344-50-4)
- 2-(Cyclopropyl(3-fluorobenzyl)amino)ethanol (CAS 1342488-86-1)
- 2-Hydrazinyl-3-methylquinolin-4(3H)-one (CAS 380665-96-3)
- 1-Benzyl-4,4-difluorocyclohexan-1-amine hydrochloride (CAS 1389313-28-3)
- 5-(4-Aminophenoxy)-2-(furan-2-ylmethyl)isoindoline-1,3-dione (CAS 310451-97-9)
- 1-(4-Fluoro-2-methylbenzyl)-1h-imidazol-2-amine (CAS 1248112-55-1)
- Semaglutide Impurity 5 (CAS 23406-82-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com