8-Bromo-2'-deoxyguanosine CAS 13389-03-2
| CAS No. | 13389-03-2 |
| Molecular Formula | C10H12BrN5O4 |
| Molecular Weight | 346.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
8-Bromo-2'-deoxyguanosine (CAS 13389-03-2), molecular formula C10H12BrN5O4 and molecular weight 346.14 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution, 8-Bromo-2'-deoxyguanosine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 346.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 8-Bromo-2'-deoxyguanosine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12BrN5O4 |
| Molecular Weight | 346.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 5 |
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Recommended Standards
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- 2-(Aminomethyl)-5-chloro-6-methylpyrimidin-4-ol (CAS 944898-29-7)
- Methyl 5-(benzyloxy)pyrazolo[1,5-a]pyridine-3-carboxylate (CAS 866216-17-3)
- Menthone, mixture of isomers (CAS 10458-14-7)
- 4-(4-Methyl-1H-imidazol-5-yl)piperidine (CAS 155511-82-3)
- 1-((3-Bromothiophen-2-yl)methyl)-1h-pyrazol-4-amine (CAS 1249819-10-0)
- Methyl 6-methyl-4-(naphthalen-1-yl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 314051-89-3)
- Garcinone C (CAS 76996-27-5)
- 2-(6-Methylpyridin-3-yl)ethan-1-amine (CAS 90196-84-2)
- 2-Methyl-5-(1,2,3-thiadiazol-4-yl)phenylamine (CAS 947013-65-2)
- Semaglutide Impurity 151 xTFA (CAS CATO-C4X-2226151)
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