6-Chloro-2-(difluoromethyl)quinolin-4(1H)-one CAS 1339490-19-5
| CAS No. | 1339490-19-5 |
| Molecular Formula | C10H6ClF2NO |
| Molecular Weight | 229.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Chloro-2-(difluoromethyl)quinolin-4(1H)-one (CAS 1339490-19-5) is a high-purity analytical reference standard with the molecular formula C10H6ClF2NO and a molecular weight of 229.61 g/mol.
The molecular framework of 6-Chloro-2-(difluoromethyl)quinolin-4(1H)-one (C10H6ClF2NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 6-Chloro-2-(difluoromethyl)quinolin-4(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H6ClF2NO |
| Molecular Weight | 229.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- (2-Chloro-7,8-difluoroquinolin-4-yl)methanol (CAS 1125702-53-5)
- 4-Chloro-6-(difluoromethoxy)quinoline (CAS 1156601-91-0)
- 3-chloro-3-[3-(difluoromethoxy)phenyl]prop-2-enenitrile (CAS 1158127-34-4)
- 5-Chloro-3-(methylthio)-6-(trifluoromethyl)-1,2,4-triazine (CAS 1196152-33-6)
- 3-Chloro-5-(3,5-difluorobenzyl)-1H-1,2,4-triazole (CAS 1219577-81-7)
- 3-Chloro-4-(difluoromethyl)quinolin-2(1H)-one (CAS 1713713-47-3)
- 3-Chloro-2-mercapto-5-(trifluoromethyl)pyridine 1-oxide (CAS 1823184-14-0)
- 1-Chloro-5-(difluoromethoxy)isoquinoline (CAS 630422-86-5)
Recommended Standards
- 4-(Chloromethyl)-1-(2,3-difluorophenyl)-1H-1,2,3-triazole (CAS 1251343-79-9)
- 5-Amino-2-chloro-6-(trifluoromethyl)pyrimidine-4(3H)-thione (CAS 1480-67-7)
- 4-(Chloromethyl)-1-(3,4-difluorophenyl)-1H-1,2,3-triazole (CAS 1250228-16-0)
- 5-Amino-6-chloro-2-(trifluoromethyl)-1H-pyrimidine-4-thione (CAS 1598-59-0)
- 5-Amino-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid (CAS 2231675-87-7)
- 1-Fluoro-4-(5,5,5-trifluoropentyl)benzene (CAS 1099598-03-4)
- Pibrentasvir (CAS 1353900-92-1)
- Methyl 3-(5-amino-2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)propanoate (CAS 1256346-74-3)
- tert-Butyl 4-(trifluoromethyl)piperazine-1-carboxylate (CAS 1415564-92-9)
- 1-(propan-2-yl)-1H-indazol-6-amine (CAS 938514-13-7)
- Quality control samples for analysis of chloroform and carbon tetrachloride in drinking water (CAS CATO-CQCM102139)
- Cefcapene Impurity 63 (CAS CATO-C4X-182463)
- 6-Bromopyridazine-3-carboxamide (CAS 1421313-70-3)
- (Tyr?)-C-Peptide (dog) (CAS 101135-67-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com