1-(2,2-Difluoroethyl)azetidine-3-carboxylic acid CAS 1339602-50-4
| CAS No. | 1339602-50-4 |
| Molecular Formula | C6H9F2NO2 |
| Molecular Weight | 165.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(2,2-Difluoroethyl)azetidine-3-carboxylic acid is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(2,2-Difluoroethyl)azetidine-3-carboxylic acid (CAS 1339602-50-4) is a high-purity analytical reference standard with the molecular formula C6H9F2NO2 and a molecular weight of 165.14 g/mol.
Structurally, 1-(2,2-Difluoroethyl)azetidine-3-carboxylic acid (C6H9F2NO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 2.0, corresponding to approximately 2 ring(s) or double-bond equivalent(s). With a molecular weight of 165.14 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(2,2-Difluoroethyl)azetidine-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H9F2NO2 |
| Molecular Weight | 165.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoroethyl Standards
- n-(2,2-Difluoroethyl)oxan-4-amine (CAS 1183014-98-3)
- 1-(2,2-Difluoroethyl)piperidin-4-ol (CAS 1248029-58-4)
- (S)-(1-(2,2-Difluoroethyl)pyrrolidin-2-yl)methanol (CAS 1568002-74-3)
- (R)-(1-(2,2-Difluoroethyl)pyrrolidin-2-yl)methanol (CAS 1568029-94-6)
- 1-(2,2-Difluoroethyl)piperidin-4-amine (CAS 1119499-74-9)
- [1-(2,2-difluoroethyl)pyrrolidin-2-yl]methanamine (CAS 1179299-77-4)
- 1-(2,2-Difluoroethyl)-1,4-diazepane (CAS 1182782-23-5)
- 2-(1,1-difluoroethyl)pyridin-4-amine (CAS 1211586-93-4)
Recommended Standards
- (S)-4,4-difluoro-1-methylpyrrolidine-2-carboxylic acid (CAS 1305325-21-6)
- (2S)-4,4-Difluoro-2-methylpyrrolidine-2-carboxylic acid (CAS 1363384-65-9)
- 3,3-Difluoro-4-piperidinecarboxylic acid (CAS 1303974-04-0)
- 5,7-difluoroisoquinoline (CAS 1369186-67-3)
- 2-[2-(hydroxymethyl)pyrrolidin-1-yl]pyridine-4-carboxylic acid (CAS 1247361-28-9)
- Methyl 4-amino-3-chloro-2,5-difluorobenzoate (CAS 2649788-89-4)
- 1-(3-Fluorophenyl)-3-oxocyclohexanecarbonitrile (CAS 1956331-06-8)
- 1-[4-(Chloromethyl)phenyl]-1H-pyrazole (CAS 143426-52-2)
- 2-(3-Isopropoxyphenyl)quinoline-4-carbohydrazide (CAS 524733-45-7)
- 4-((Tetrahydrofuran-2-yl)methyl)piperidin-4-ol (CAS 2090429-43-7)
- Paracetamol (CAS 103-90-2)
- N-(2-chlorophenyl)-4-(1H-pyrrol-1-yl)-1,3,5-triazin-2-amine (CAS 438249-81-1)
- 1-[2-(1H-1,2,4-triazol-1-yl)ethyl]piperazine dihydrochloride (CAS 1334146-67-6)
- Semaglutide Impurity 4 (CAS CATO-C4X-22264)
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