4-Cyclobutoxy-3,5-difluorobenzoic acid CAS 1339696-85-3
| CAS No. | 1339696-85-3 |
| Molecular Formula | C11H10F2O3 |
| Molecular Weight | 228.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Cyclobutoxy-3,5-difluorobenzoic acid (C11H10F2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
4-Cyclobutoxy-3,5-difluorobenzoic acid (CAS 1339696-85-3), molecular formula C11H10F2O3 and molecular weight 228.19 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Cyclobutoxy-3,5-difluorobenzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H10F2O3 |
| Molecular Weight | 228.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
Related Cyclobutoxy Standards
- 3-Cyclobutoxy-2-methylpropane-1-sulfonyl chloride (CAS 1343870-02-9)
- 2-Cyclobutoxy-4,6-dimethylpyridine-3-carboxylic acid (CAS 1247523-42-7)
- 5-Cyclobutoxy-2-(propan-2-yl)pyrimidine-4-carboxylic acid (CAS 1457497-47-0)
- 5-Cyclobutoxy-6-nitrobenzo[d][1,3]dioxole (CAS 1706465-13-5)
- 3-Cyclobutoxy-2,2-dimethylpropane-1-sulfonyl chloride (CAS 1496824-86-2)
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- 4-Cyclobutoxy-3-(difluoromethyl)aniline (CAS 1341556-46-4)
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Recommended Standards
- 1-(2,6-Difluorophenyl)-2-(1,3-dioxolan-2-yl)ethan-1-one (CAS 1263366-03-5)
- 2-(3,4-Difluorophenyl)tetrahydrofuran-3-carboxylic acid (CAS 1340448-77-2)
- 1-(3,4-Difluorophenyl)-2-(1,3-dioxolan-2-yl)ethan-1-one (CAS 1263365-98-5)
- 4-(Cyclopropylmethoxy)-3,5-difluorobenzoic acid (CAS 1343436-42-9)
- 7-bromo-3,5-dimethyl-2,3-dihydro-1,3-benzoxazol-2-one (CAS 1226069-01-7)
- 2-Chloro-1-fluoro-3-(trichloromethoxy)benzene (CAS 1404193-79-8)
- 6-ethyl-2-oxo-1,2,5,6,7,8-hexahydroquinoline-3-carbonitrile (CAS 1249858-53-4)
- Cotinine glucuronide (CAS 139427-57-9)
- Lusutrombopag Impurity 32 (CAS CATO-C4X-208432)
- 5-Methoxynicotinoyl chloride (CAS 1123782-83-1)
- 3-(Boc-amino)butanoic Acid (CAS 52815-19-7)
- (3-Aminobenzofuran-2-yl)(2,4-dichlorophenyl)methanone (CAS 882864-70-2)
- 4'-Methoxy-[1,1'-biphenyl]-3-carbaldehyde (CAS 118350-17-7)
- Insulin Degludec Impurity 15 (CAS CATO-C4X-215715)
Why CATO?
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