Amiodarone Impurity 32 CAS 134-92-9

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.134-92-9
Molecular FormulaC14H12O2
Molecular Weight212.24 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Amiodarone Impurity 32 CAS 134-92-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 212.24 g/mol gives Amiodarone Impurity 32 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Amiodarone Impurity 32 (CAS 134-92-9) is a certified pharmaceutical impurity reference standard with the molecular formula C14H12O2 and a molecular weight of 212.24 g/mol.

Amiodarone Impurity 32 (C14H12O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Amiodarone Impurity 32 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H12O2
Molecular Weight212.24 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957

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