Telmisartan Impurity 54 CAS 7148-03-0
| CAS No. | 7148-03-0 |
| Molecular Formula | C14H12O2 |
| Molecular Weight | 212.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Telmisartan Impurity 54.
As a process- or degradation-related impurity, Telmisartan Impurity 54 (CAS 7148-03-0, C14H12O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Telmisartan Impurity 54 (C14H12O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Telmisartan Impurity 54 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H12O2 |
| Molecular Weight | 212.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
Related Telmisartan Standards
- Telmisartan Impurity N3 (CAS 171863-96-0)
- Telmisartan Impurity 28 (CAS 152628-03-0)
- Telmisartan Impurity 69 (CAS CATO-C4X-135969)
- Telmisartan Impurity 59 (CAS 1016696-74-4)
- Telmisartan Impurity 98 (CAS CATO-C4X-135998)
- Telmisartan Impurity 99 (CAS CATO-C4X-135999)
- Telmisartan Aldehyde Impurity (CAS 112804-58-7)
- Telmisartan Impurity 33 (CAS 114772-34-8)
Recommended Standards
- Dexmedetomidine Impurity 61 (CAS 720-75-2)
- Amiodarone Impurity 32 (CAS 134-92-9)
- Valproate impurity 90 (CAS CATO-C4X-116690)
- Flurbiprofen Impurity 162 (CAS 861795-19-9)
- Cetirizine EP Impurity A (CAS 303-26-4)
- Chlorthalidone Impurity N1 (CAS 5543-24-8)
- Olanzapine Impurity 57 (CAS CATO-C4X-117857)
- Ethyl 4-(3-chloropropyl)piperazine-1-carboxylate (CAS 74571-66-7)
- ethyl 2-(5-methyl-2-oxo-octahydro-1,3-benzoxazol-3-yl)acetate (CAS 1222885-85-9)
- n-(1-(Pyridin-3-yl)ethyl)butan-2-amine (CAS 1019500-56-1)
- 1-(4-Chloro-3-fluorobenzyl)-1h-imidazol-2-amine (CAS 1251109-01-9)
- D,L-Tosylisopropylideneglycerol-d5 (CAS 1330076-68-0)
- 3-Hydroxy-5-iodobenzoic acid (CAS 50765-21-4)
- Tirzepatide Impurity 44 (CAS CATO-C4X-324044)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com