5-Chloro-4-fluoro-2-(trifluoromethyl)benzaldehyde CAS 134099-23-3
| CAS No. | 134099-23-3 |
| Molecular Formula | C8H3ClF4O |
| Molecular Weight | 226.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 5-Chloro-4-fluoro-2-(trifluoromethyl)benzaldehyde (C8H3ClF4O) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 226.56 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
5-Chloro-4-fluoro-2-(trifluoromethyl)benzaldehyde (CAS 134099-23-3), molecular formula C8H3ClF4O and molecular weight 226.56 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H3ClF4O |
| Molecular Weight | 226.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 5-Chloro-2-fluoro-3-(trifluoromethyl)benzaldehyde (CAS 117752-05-3)
- 1-(2-Chloro-6-fluorophenyl)-2,2,2-trifluoroethan-1-one (CAS 1208077-59-1)
- 3-Chloro-2-fluoro-4-(trifluoromethyl)benzaldehyde (CAS 134099-21-1)
- 2-Chloro-4-fluoro-6-(trifluoromethyl)benzaldehyde (CAS 134099-27-7)
- 3-Chloro-4-fluoro-5-(trifluoromethyl)benzaldehyde (CAS 134099-29-9)
- 5-Chloro-2-fluoro-4-(trifluoromethyl)benzaldehyde (CAS 134099-32-4)
- 2-Chloro-1-(3,4-difluorophenyl)-2,2-difluoroethan-1-one (CAS 1352215-14-5)
- 2-Chloro-1-(3,5-difluorophenyl)-2,2-difluoroethan-1-one (CAS 1352232-06-4)
Recommended Standards
- 126917-10-0 2 - Fluoro - 4 - (trifluoromethyl)benzoyl chloride 2-Fluoro-4-trifluoromethyl-benzoyl chloride 2-fluoro-4-(trifluoromethyl)benzoyl chloride 2-fluoro-4-(trifluoromethyl)benzoyl chloride 97% 2-fluoro-4-(trifluoromethyl)benzoyl chloride, 97% 1gr 2-fluoro-4-(trifluoromethyl)benzoylchloride97% 2-fluoro-4-trifluoromethyl-1-benzenecarbonyl chloride 4-trifluoromethyl-2-fluorobenzoyl chloride alpha,alpha,alpha,2-tetrafluoro-p-toluoyl chloride benzoyl chloride, 2-fluoro-4-(trifluoromethyl)- currency, currency, currency,2-tetrafluoro-p-toluoyl chloride (CAS 126917-10-0)
- 109227-12-5 2-FLUORO-6-(TRIFLUOROMETHYL)BENZOYL CHLORIDE 2-Fluoro-6-(trifluoromethyl)benzoylchloride ALPHA,ALPHA,ALPHA,6-TETRAFLUORO-O-TOLUOYL CHLORIDE AS00068 ATTERCOP-CHM AT107063 OTF-BOC-6F (CAS 109227-12-5)
- 4-Chloro-6-(trifluoromethyl)pyrimidine-5-carboxylic acid (CAS 887626-22-4)
- 4-Chloro-3-fluoro-5-(trifluoromethyl)benzaldehyde (CAS 1431329-67-7)
- 2',3',4',5'-Tetrahydro-[1,1'-biphenyl]-2-amine (CAS 46175-80-8)
- 3-Chloro-6-methylpyrazine-2-carbaldehyde (CAS 1384678-57-2)
- 3-(tert-Butyldimethylsilyloxy)propan-1-amine (CAS 115306-75-7)
- 3,3'-(1,4-Diazepane-1,4-diyl)bis(1,1,1-trifluoropropan-2-ol) (CAS 477847-09-9)
- 7-cyclopropyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine (CAS 885949-41-7)
- 2-Acetamido-2-deoxy-3-O-(α-L-fucopyranosyl)-D-glucopyranose Pentaacetate (CAS 309263-13-6)
- 2-Cyano-N-(2,4-difluorophenyl)acetamide (CAS 1961-38-2)
- 3-(Pyrrolidin-3-yloxy)aniline (CAS 1123169-07-2)
- 2-(tert-Butyl)-4-chloro-1-cyclopropoxybenzene (CAS 1243326-38-6)
- (Des-Gly2)-Exenatide trifluoroacetate salt (CAS 1678416-78-8)
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