2-Chloro-4-fluoro-6-(trifluoromethyl)benzaldehyde CAS 134099-27-7
| CAS No. | 134099-27-7 |
| Molecular Formula | C8H3ClF4O |
| Molecular Weight | 226.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Chloro-4-fluoro-6-(trifluoromethyl)benzaldehyde (C8H3ClF4O) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 2-Chloro-4-fluoro-6-(trifluoromethyl)benzaldehyde (CAS 134099-27-7), a certified reference material (molecular formula C8H3ClF4O, MW 226.56 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Chloro-4-fluoro-6-(trifluoromethyl)benzaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H3ClF4O |
| Molecular Weight | 226.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 5-Chloro-2-fluoro-3-(trifluoromethyl)benzaldehyde (CAS 117752-05-3)
- 1-(2-Chloro-6-fluorophenyl)-2,2,2-trifluoroethan-1-one (CAS 1208077-59-1)
- 3-Chloro-2-fluoro-4-(trifluoromethyl)benzaldehyde (CAS 134099-21-1)
- 5-Chloro-4-fluoro-2-(trifluoromethyl)benzaldehyde (CAS 134099-23-3)
- 3-Chloro-4-fluoro-5-(trifluoromethyl)benzaldehyde (CAS 134099-29-9)
- 5-Chloro-2-fluoro-4-(trifluoromethyl)benzaldehyde (CAS 134099-32-4)
- 2-Chloro-1-(3,4-difluorophenyl)-2,2-difluoroethan-1-one (CAS 1352215-14-5)
- 2-Chloro-1-(3,5-difluorophenyl)-2,2-difluoroethan-1-one (CAS 1352232-06-4)
Recommended Standards
- 126917-10-0 2 - Fluoro - 4 - (trifluoromethyl)benzoyl chloride 2-Fluoro-4-trifluoromethyl-benzoyl chloride 2-fluoro-4-(trifluoromethyl)benzoyl chloride 2-fluoro-4-(trifluoromethyl)benzoyl chloride 97% 2-fluoro-4-(trifluoromethyl)benzoyl chloride, 97% 1gr 2-fluoro-4-(trifluoromethyl)benzoylchloride97% 2-fluoro-4-trifluoromethyl-1-benzenecarbonyl chloride 4-trifluoromethyl-2-fluorobenzoyl chloride alpha,alpha,alpha,2-tetrafluoro-p-toluoyl chloride benzoyl chloride, 2-fluoro-4-(trifluoromethyl)- currency, currency, currency,2-tetrafluoro-p-toluoyl chloride (CAS 126917-10-0)
- 4-Chloro-3-fluoro-5-(trifluoromethyl)benzaldehyde (CAS 1431329-67-7)
- 109227-12-5 2-FLUORO-6-(TRIFLUOROMETHYL)BENZOYL CHLORIDE 2-Fluoro-6-(trifluoromethyl)benzoylchloride ALPHA,ALPHA,ALPHA,6-TETRAFLUORO-O-TOLUOYL CHLORIDE AS00068 ATTERCOP-CHM AT107063 OTF-BOC-6F (CAS 109227-12-5)
- 3-Chloro-2-fluoro-6-(trifluoromethyl)benzaldehyde (CAS 186517-29-3)
- 2-((5-(Benzo[d][1,3]dioxol-5-yl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-1-phenylethan-1-one (CAS 325694-50-6)
- 3-(Aminomethyl)-5-(4-pyridyl)pyrazole (CAS 1004303-48-3)
- Ethyl 4-oxo-4,9a-dihydro-1H-pyrimido[1,2-a]pyrimidine-3-carboxylate (CAS 40519-95-7)
- 2-Iodo-5-(trifluoromethoxy)pyridine (CAS 1221171-87-4)
- Pentoxifylline EP Impurity E (CAS 77196-87-3)
- Fenfluthrin (CAS 75867-00-4)
- Mianserin Impurity 97 (CAS 85141-92-0)
- Benzhexol Impurity 8 (CAS 6853-22-1)
- (R)-Methyl 3-iodo-4,5,6,7-tetrahydro-1H-indazole-6-carboxylate (CAS 1980784-07-3)
- Semaglutide impurity 271 (CAS CATO-C4X-2226271)
Why CATO?
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