2,2,2-Trifluoro-1-(4'-methoxy-[1,1'-biphenyl]-4-yl)ethan-1-one CAS 134249-43-7

Purity 97%+In StockPharmaceutical Standards
CAS No.134249-43-7
Molecular FormulaC15H11F3O2
Molecular Weight280.24 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,2,2-Trifluoro-1-(4'-methoxy-[1,1'-biphenyl]-4-yl)ethan-1-one CAS 134249-43-7 chemical structure

Description

The occurrence of 2,2,2-Trifluoro-1-(4'-methoxy-[1,1'-biphenyl]-4-yl)ethan-1-one is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 2,2,2-Trifluoro-1-(4'-methoxy-[1,1'-biphenyl]-4-yl)ethan-1-one (CAS 134249-43-7), a certified reference material (molecular formula C15H11F3O2, MW 280.24 g/mol) for analytical method development and quality control.

Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system, 2,2,2-Trifluoro-1-(4'-methoxy-[1,1'-biphenyl]-4-yl)ethan-1-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 280.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC15H11F3O2
Molecular Weight280.24 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF-containing

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