Methyl 4'-(trifluoromethyl)-[1,1'-biphenyl]-4-carboxylate CAS 127783-73-7

Purity 97%+In StockPharmaceutical Standards
CAS No.127783-73-7
Molecular FormulaC15H11F3O2
Molecular Weight280.24 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Methyl 4'-(trifluoromethyl)-[1,1'-biphenyl]-4-carboxylate CAS 127783-73-7 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 4'-(trifluoromethyl)-[1,1'-biphenyl]-4-carboxylate.

Methyl 4'-(trifluoromethyl)-[1,1'-biphenyl]-4-carboxylate (CAS 127783-73-7) is a high-purity analytical reference standard with the molecular formula C15H11F3O2 and a molecular weight of 280.24 g/mol.

The molecular framework of Methyl 4'-(trifluoromethyl)-[1,1'-biphenyl]-4-carboxylate (C15H11F3O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC15H11F3O2
Molecular Weight280.24 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1993
Halogen ContentF-containing

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