3-Bromo-1-(2-fluorophenyl)piperidin-2-one CAS 1342838-72-5

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Bromo-1-(2-fluorophenyl)piperidin-2-one.

CATO supplies 3-Bromo-1-(2-fluorophenyl)piperidin-2-one (CAS 1342838-72-5), a certified reference material (molecular formula C11H11BrFNO, MW 272.11 g/mol) for analytical method development and quality control.

The molecular framework of 3-Bromo-1-(2-fluorophenyl)piperidin-2-one (C11H11BrFNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-Bromo-1-(2-fluorophenyl)piperidin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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