1-(2,2-Difluoroethyl)piperidine-4-carbonitrile CAS 1343312-26-4
| CAS No. | 1343312-26-4 |
| Molecular Formula | C8H12F2N2 |
| Molecular Weight | 174.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrile group, fluorine substitution, 1-(2,2-Difluoroethyl)piperidine-4-carbonitrile is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 174.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
1-(2,2-Difluoroethyl)piperidine-4-carbonitrile (CAS 1343312-26-4), molecular formula C8H12F2N2 and molecular weight 174.19 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(2,2-Difluoroethyl)piperidine-4-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H12F2N2 |
| Molecular Weight | 174.19 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoroethyl Standards
- 4-(1,1-Difluoroethyl)benzenethiol (CAS 1892499-40-9)
- 3-(1,1-Difluoroethyl)benzenethiol (CAS 1896970-19-6)
- 4-(1,1-Difluoroethyl)-2-fluoro-1-methylbenzene (CAS 1138445-12-1)
- 2-(1,1-Difluoroethyl)-1-fluoro-4-methylbenzene (CAS 1138445-13-2)
- 1-(2,2-Difluoroethyl)-3-methyl-1h-pyrazole-4-carbaldehyde (CAS 1006487-14-4)
- 1-(2,2-Difluoroethyl)-5-methyl-1h-pyrazole-4-carbaldehyde (CAS 1170655-68-1)
- 1-(1-(2,2-Difluoroethyl)-1H-pyrazol-4-yl)ethan-1-one (CAS 1341285-03-7)
- 1-(1-(2,2-Difluoroethyl)-1H-pyrazol-3-yl)ethan-1-one (CAS 1855688-22-0)
Recommended Standards
- Methyl 2-hydroxy-2-(tetrahydro-2h-pyran-3-yl)acetate (CAS 1341680-43-0)
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- N-Nitroso Guvacoline-d4 (CAS 1330277-21-8)
- 2-(3-Hydroxyoxolan-3-yl)-2-methylpropanoic acid (CAS 1344156-26-8)
- Dimethyl 5-Chloroisophthalate (CAS 20330-90-9)
- 3,4-dihydro-2H-1,5-benzoxathiepin-3-one (CAS 112632-24-3)
- 2-(Pyrimidin-2-ylamino)-propionic acid (CAS 126190-31-6)
- cis-2-methylpiperidine-4-carboxylic acid;hydrochloride (CAS 1807912-30-6)
- 1,8-Di(acridin-9-yl)octane (CAS 141946-29-4)
- 6-Fluoro-1-methyl-1,2,3,4-tetrahydroquinoline (CAS 388078-35-1)
- 2-(2-Hydroxy-3-oxobutan-2-yl)-2,5-dimethylfuran-3(2H)-one (CAS 10410-20-5)
- ethyl 1-(4-chloro-2-fluorophenyl)-1H,4H,5H,6H-cyclopenta[c]pyrazole-3-carboxylate (CAS 1909317-05-0)
- Phenyl 2-(benzylthio)-1H-benzo[d]imidazole-1-carboxylate (CAS 845879-38-1)
- Tirzepatide Impurity 12 (CAS CATO-C4X-324012)
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