4-(1,1-Difluoroethyl)benzenethiol CAS 1892499-40-9
| CAS No. | 1892499-40-9 |
| Molecular Formula | C8H8F2S |
| Molecular Weight | 174.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(1,1-Difluoroethyl)benzenethiol (C8H8F2S) contains sulfur-containing functionality, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
4-(1,1-Difluoroethyl)benzenethiol (CAS 1892499-40-9), molecular formula C8H8F2S and molecular weight 174.21 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8F2S |
| Molecular Weight | 174.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Difluoroethyl Standards
- 3-(1,1-Difluoroethyl)benzenethiol (CAS 1896970-19-6)
- 1-(2,2-Difluoroethyl)piperidine-4-carbonitrile (CAS 1343312-26-4)
- 4-(1,1-Difluoroethyl)-2-fluoro-1-methylbenzene (CAS 1138445-12-1)
- 2-(1,1-Difluoroethyl)-1-fluoro-4-methylbenzene (CAS 1138445-13-2)
- 1-(2,2-Difluoroethyl)-3-methyl-1h-pyrazole-4-carbaldehyde (CAS 1006487-14-4)
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- 1-(1-(2,2-Difluoroethyl)-1H-pyrazol-4-yl)ethan-1-one (CAS 1341285-03-7)
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Recommended Standards
- (2,4-Difluoro-3-methylphenyl)(methyl)sulfane (CAS 1807192-63-7)
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- (3,4-Difluorophenyl)(ethyl)sulfane (CAS 863505-15-1)
- 1-Methyl-L-histidine-d5Discontinued, please see T779353 (CAS 1795786-96-7)
- 1,3,5-Trimethylpyrimidine-2,4(1H,3H)-dione (CAS 4401-71-2)
- (3S,5R)-3-Amino-5-hydroxy-piperidine-1-carboxylic acid benzyl ester (CAS 2165622-15-9)
- 1-(3-Bromo-5-fluorobenzyl)-1h-1,2,4-triazol-3-amine (CAS 1508220-36-7)
- 2-(5-aminopyridazin-3-yl)ethanol (CAS 1896626-48-4)
- Methyl (R)-3-amino-2-((tert-butoxycarbonyl)amino)propanoate Oxalate (CAS 130622-06-9)
- 6-Chloro-3-(chloromethyl)imidazo[1,2-a]pyrimidine (CAS 944906-66-5)
- 3-(Trifluoromethyl)pyrrolidin-3-ol Hydrochloride (CAS 1334147-81-7)
- 4-(3-Nitrophenoxy)benzonitrile (CAS 55368-17-7)
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- Semaglutide impurity 55 (CAS CATO-C4X-222655)
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