4-Amino-1-(4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(thiophen-2-yl)pyrimidin-2(1H)-one CAS 134333-67-8
| CAS No. | 134333-67-8 |
| Molecular Formula | C13H15N3O4S |
| Molecular Weight | 309.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Amino-1-(4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(thiophen-2-yl)pyrimidin-2(1H)-one.
4-Amino-1-(4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(thiophen-2-yl)pyrimidin-2(1H)-one (CAS 134333-67-8), molecular formula C13H15N3O4S and molecular weight 309.34 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-Amino-1-(4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(thiophen-2-yl)pyrimidin-2(1H)-one (C13H15N3O4S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 309.34 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H15N3O4S |
| Molecular Weight | 309.34 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 4-Amino-7-(((1,3-dihydroxypropan-2-yl)oxy)methyl)-6-(methylthio)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (CAS 127945-86-2)
- Ethyl 5-amino-1-(3-(methylsulfonyl)phenyl)-1H-pyrazole-3-carboxylate (CAS 1367842-55-4)
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Recommended Standards
- 2-((3,5-Dimethoxyphenyl)amino)pyridine-3-sulfonamide (CAS 1340970-16-2)
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- 2-((3,4-Dimethoxyphenyl)amino)pyridine-3-sulfonamide (CAS 1340859-13-3)
- 1-{4-[(2E)-3-(2-Thienyl)prop-2-enoyl]-phenyl}-1H-pyrrole-2,5-dione (CAS 1365988-69-7)
- (3-Methoxy-4-(prop-2-yn-1-yloxy)phenyl)methanol (CAS 385383-48-2)
- (S)-1-(3-fluoro-5-methylphenyl)propan-1-amine (CAS 1213621-88-5)
- N-(2-Hydroxy-1,1-dimethylethyl)-2-pyrrolidinecarboxamide hydrochloride (CAS 1236266-84-4)
- Ethyl N-Boc-3-piperidinecarboxylate (CAS 130250-54-3)
- N-(propan-2-yl)cyclobutanamine (CAS 1250638-67-5)
- (R)-2-Amino-4-bromobutanoic acid (CAS 205524-62-5)
- 2,2'-(1,2-Phenylene)bis(ethan-1-ol) (CAS 17378-99-3)
- 2H-Imidazo[4,5-d]oxazolo[4,5-b]pyridine (CAS 807364-32-5)
- 2-((4,4-Dimethylcyclohexyl)amino)propan-1-ol (CAS 1343509-20-5)
- Des-Lys20(Side Chain)-Semaglutide (CAS CATO-C4X-2226280)
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