1-([1,2,4]triazolo[4,3-a]pyrazin-8-yl)piperidin-3-amine CAS 1344005-75-9
| CAS No. | 1344005-75-9 |
| Molecular Formula | C10H14N6 |
| Molecular Weight | 218.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-([1,2,4]triazolo[4,3-a]pyrazin-8-yl)piperidin-3-amine (CAS 1344005-75-9), molecular formula C10H14N6 and molecular weight 218.26 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-([1,2,4]triazolo[4,3-a]pyrazin-8-yl)piperidin-3-amine (C10H14N6) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-([1,2,4]triazolo[4,3-a]pyrazin-8-yl)piperidin-3-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H14N6 |
| Molecular Weight | 218.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 6 |
Related triazolo Standards
- 2-methyl-1-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine (CAS 1306605-92-4)
- 1-([1,2,4]triazolo[4,3-a]pyrazin-8-yl)piperidin-4-amine (CAS 1339928-91-4)
- 2-methyl-1-{[1,2,4]triazolo[4,3-a]pyrazin-8-yl}piperazine (CAS 1342502-41-3)
- 1-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)piperidin-4-amine (CAS 1525554-57-7)
- 1-(6-Methyl-[1,2,3]triazolo[1,5-a]pyrazin-4-yl)pyrrolidin-3-amine (CAS 1707394-61-3)
- 1-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)piperidin-3-amine (CAS 2059933-08-1)
- 1-{3-methyl-[1,2,4]triazolo[4,3-a]pyrazin-8-yl}piperazine (CAS 305865-38-7)
- N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)pentanamide (CAS 338419-03-7)
Recommended Standards
- 1-(3-(4-Methoxyphenyl)-1H-1,2,4-triazol-5-yl)ethanamine (CAS 1343637-15-9)
- N1-[(6-methoxy-3-pyridyl)methyl]-N2-cyano-N1-methyl acetamidine (CAS 135410-71-8)
- 3-(Oxan-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-6-amine (CAS 1343063-60-4)
- 2-(1-Isopropyl-1H-pyrazol-4-yl)-6-methylpyrimidin-4-ol (CAS 1365942-38-6)
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