1-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)piperidin-4-amine CAS 1525554-57-7
| CAS No. | 1525554-57-7 |
| Molecular Formula | C10H14N6 |
| Molecular Weight | 218.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)piperidin-4-amine (C10H14N6) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
1-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)piperidin-4-amine (CAS 1525554-57-7), molecular formula C10H14N6 and molecular weight 218.26 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)piperidin-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H14N6 |
| Molecular Weight | 218.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 6 |
Related Triazolo Standards
- 2-methyl-1-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazine (CAS 1306605-92-4)
- 1-([1,2,4]triazolo[4,3-a]pyrazin-8-yl)piperidin-4-amine (CAS 1339928-91-4)
- 2-methyl-1-{[1,2,4]triazolo[4,3-a]pyrazin-8-yl}piperazine (CAS 1342502-41-3)
- 1-([1,2,4]triazolo[4,3-a]pyrazin-8-yl)piperidin-3-amine (CAS 1344005-75-9)
- 1-(6-Methyl-[1,2,3]triazolo[1,5-a]pyrazin-4-yl)pyrrolidin-3-amine (CAS 1707394-61-3)
- 1-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)piperidin-3-amine (CAS 2059933-08-1)
- 1-{3-methyl-[1,2,4]triazolo[4,3-a]pyrazin-8-yl}piperazine (CAS 305865-38-7)
- N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)pentanamide (CAS 338419-03-7)
Recommended Standards
- 1-{5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl}-1H-pyrazol-4-amine (CAS 1521340-43-1)
- 2-(2-ETHYL-IMIDAZOL-1-YL)-6-METHOXY-PYRIDIN-3-YLAMINE (CAS 1545522-14-2)
- 1-(4-Methoxybenzyl)-5-methyl-1H-1,2,3-triazol-4-amine (CAS 1511071-63-8)
- 2-Ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)aniline (CAS 1578247-81-0)
- 3-Bromo-N-butylbenzamide (CAS 35390-07-9)
- 2-(Difluoromethyl)-4-methoxy-5-methylpyridine-3-carboxamide (CAS 1806987-89-2)
- 4-(4-Chloro-3-nitrobenzoyl)-8-ethyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326808-44-9)
- 2-Fluoro-4,6-dimethylpyrimidine (CAS 38953-33-2)
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- Loratadine Impurity 13 (CAS CATO-C4X-142613)
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