2-Chloro-4-cyclopropylthiazole CAS 1344072-01-0
| CAS No. | 1344072-01-0 |
| Molecular Formula | C6H6ClNS |
| Molecular Weight | 159.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Chloro-4-cyclopropylthiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 2-Chloro-4-cyclopropylthiazole (CAS 1344072-01-0), a certified reference material (molecular formula C6H6ClNS, MW 159.64 g/mol) for analytical method development and quality control.
The molecular framework of 2-Chloro-4-cyclopropylthiazole (C6H6ClNS) is characterized by a nitrile group, sulfur-containing functionality, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H6ClNS |
| Molecular Weight | 159.64 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-Chloro-5-cyclopropylthiazole (CAS 1412953-26-4)
- 5-Chloro-2-cyclopropylthiazole (CAS 1849283-73-3)
- 3-chloro-2-methyl-pyridine-4-thiol (CAS 1851566-28-3)
- 2-Chloro-3-(methylthio)pyridine (CAS 65753-48-2)
- 2-Chloro-4-(methylthio)pyridine (CAS 71506-83-7)
- 2-Chloro-5-(methylthio)pyridine (CAS 41288-94-2)
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- 2-Chloro-6-(methylthio)pyridine (CAS 77145-64-3)
Recommended Standards
- 4-Amino-3-chlorobenzenethiol (CAS 1122-40-3)
- 2-Amino-4-chlorobenzenethiol (CAS 1004-00-8)
- 2-Amino-6-chlorobenzenethiol (CAS 14482-33-8)
- 3296-05-7 AR-1J7221 n-(2-(dimethylamino)ethyl)-n'-(2-((2-(dimethylamino)ethyl)methylamino)ethyl)-n,n'-dimethylethylenediamine (CAS 3296-05-7)
- 2-(Difluoromethyl)-3-iodo-5-methylpyridine-6-acetonitrile (CAS 1807137-47-8)
- 4-(2,6-Dimethoxypyrimidin-4-yl)-N-(3-(trifluoromethyl)phenyl)piperazine-1-carboxamide (CAS 1021214-73-2)
- 1-Bromo-2-chloro-3-nitro-5-(trifluoromethyl)benzene (CAS 1881331-27-6)
- Dimethyl 2-(cyclopropylmethylene)malonate (CAS 70064-01-6)
- 2-Methoxybenzenesulfonyl chloride (CAS 10130-87-7)
- Benidipine Impurity 59 (CAS 61311-83-9)
- 2-((Cyanomethyl)amino)ethanesulfonic acid (CAS 776249-60-6)
- tert-Butyl 2-cyano-2-(trifluoromethyl)pyrrolidine-1-carboxylate (CAS 2095409-30-4)
- 1,2,3,5-Tetrachloronaphthalene (CAS 53555-63-8)
- ([D2]Gly4)-Cholecystokinin Octapeptide (sulfated) ammonium salt (CAS 1926163-74-7)
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