2-Amino-6-chlorobenzenethiol CAS 14482-33-8
| CAS No. | 14482-33-8 |
| Molecular Formula | C6H6ClNS |
| Molecular Weight | 159.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Amino-6-chlorobenzenethiol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-Amino-6-chlorobenzenethiol (CAS 14482-33-8), molecular formula C6H6ClNS and molecular weight 159.64 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrile group, sulfur-containing functionality, chlorine substitution, an aromatic ring system, 2-Amino-6-chlorobenzenethiol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 159.64 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H6ClNS |
| Molecular Weight | 159.64 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 2-Amino-4-chlorobenzenethiol (CAS 1004-00-8)
- 4-Amino-3-chlorobenzenethiol (CAS 1122-40-3)
- 4-Amino-2-chlorobenzene-1-thiol (CAS 15178-53-7)
- 3-Amino-2-chlorobenzenethiol (CAS 1801694-22-3)
- 2-Amino-3-chlorobenzenethiol (CAS 40925-72-2)
- 2-Amino-5-chlorobenzenethiol (CAS 23474-98-8)
- 5-Amino-2-chlorobenzenethiol (CAS 97094-83-2)
- 4-amino-2-chloro-pyridine-3-carbonitrile (CAS 1194341-42-8)
Recommended Standards
- 2-Chloro-5-cyclopropylthiazole (CAS 1412953-26-4)
- 2-Chloro-4-cyclopropylthiazole (CAS 1344072-01-0)
- 5-Chloro-2-cyclopropylthiazole (CAS 1849283-73-3)
- 3-chloro-2-methyl-pyridine-4-thiol (CAS 1851566-28-3)
- 4-(2-Methoxyethyl)-5-(2-phenylphenoxymethyl)-4H-1,2,4-triazole-3-thiol (CAS 722464-29-1)
- 6-Methoxy-3-(((2-methylphenethyl)amino)methyl)quinolin-2(1H)-one (CAS 917562-12-0)
- methyl 2-hydroxy-3-(2-methylprop-2-en-1-yl)benzoate (CAS 92847-95-5)
- (2'-Chloro-[1,1'-biphenyl]-4-yl)methanol (CAS 109524-03-0)
- Brexpiprazole Impurity 100 (CAS CATO-C4X-1131100)
- 1-(1-Methyl-1H-1,2,4-triazol-5-yl)ethan-1-amine (CAS 1210875-52-7)
- Perampanel Impurity 8 (CAS CATO-C4X-24308)
- methyl 7-bromo-5-ethyl-1H-pyrazolo[4,3-d]pyrimidine-3-carboxylate (CAS 2091582-11-3)
- 4-(Diisopropylamino)butan-1-ol (CAS 103859-38-7)
- Exenatide (CAS 141758-74-9（free base）)
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