Triclosan Impurity 7 CAS 134479-47-3
| CAS No. | 134479-47-3 |
| Molecular Formula | C10H8Cl2O2 |
| Molecular Weight | 231.08 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 231.08 g/mol gives Triclosan Impurity 7 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Triclosan Impurity 7 (CAS 134479-47-3) is a certified pharmaceutical impurity reference standard with the molecular formula C10H8Cl2O2 and a molecular weight of 231.08 g/mol.
Structurally, Triclosan Impurity 7 (C10H8Cl2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 231.08 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Triclosan Impurity 7 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8Cl2O2 |
| Molecular Weight | 231.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
Related Triclosan Standards
- Triclosan Impurity 8 (CAS CATO-C4X-25048)
- Triclosan Impurity 5 (CAS 67028-17-5)
- Triclosan (CAS 3380-34-5)
- Triclosan-d3 (2,4-dichlorophenoxy-d3) (CAS 1020719-98-5)
- Triclosan-13C6 (CAS CATO-CCHM704075)
- Triclosan Methyl Ether (CAS 4640-01-1)
- Triclosan Impurity 4 (CAS 546127-65-5)
- Triclosan methyl D3 (methoxy D3) (CAS 1020720-00-6)
Recommended Standards
- Lifitegrast Impurity 62 (CAS CATO-C4X-240962)
- 95609-48-6 2(3H)-Furanone, 5-(3,4-dichlorophenyl)dihydro- DTXSID10430798 (CAS 95609-48-6)
- (R)-2-Bromo-1-(3-methoxyphenyl)ethan-1-ol (CAS 100306-27-2)
- trans-2-(2,3-Dichlorophenyl)cyclopropanecarboxylic Acid (CAS 2044705-94-2)
- Posaconazole Impurity 30 (CAS CATO-C4X-120830)
- Indobufen impurity 77 (CAS CATO-C4X-179277)
- Cefotiam Impurity 44 (CAS CATO-C4X-120444)
- Vonoprazan Impurity 150 (CAS 312307-69-0)
- 2-Chloro-6-(trifluoromethoxy)benzamide (CAS 1261861-53-3)
- 5-(Aminomethyl)-6-methylpyridin-2(1H)-one (CAS 173261-66-0)
- 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one (CAS 76282-95-6)
- 1,3-Bis(1H-benzo[d][1,2,3]triazol-1-yl)-2-methylpropane-1,3-dione (CAS 852865-91-9)
- 2,6-Dichlorophenyl-4'-nitrophenyl ether (CAS 2093-28-9)
- Semaglutide impurity 109 (CAS CATO-C4X-2226109)
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