5-(Difluoromethyl)indoline-2,3-dione CAS 1344890-69-2
| CAS No. | 1344890-69-2 |
| Molecular Formula | C9H5F2NO2 |
| Molecular Weight | 197.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-(Difluoromethyl)indoline-2,3-dione is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-(Difluoromethyl)indoline-2,3-dione (CAS 1344890-69-2) is a high-purity analytical reference standard with the molecular formula C9H5F2NO2 and a molecular weight of 197.14 g/mol.
Based on its molecular formula C9H5F2NO2, 5-(Difluoromethyl)indoline-2,3-dione contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 197.14 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(Difluoromethyl)indoline-2,3-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H5F2NO2 |
| Molecular Weight | 197.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoromethyl Standards
- 7-(Difluoromethyl)indoline-2,3-dione (CAS 1344894-30-9)
- 6-(Difluoromethyl)indoline-2,3-dione (CAS 1344904-59-1)
- 2-(Difluoromethyl)pyrido[3,4-d]pyrimidin-4(3H)-one (CAS 1437482-82-0)
- 2-(Difluoromethyl)benzo[d]oxazole-4-carboxaldehyde (CAS 1804192-31-1)
- 4-(Difluoromethyl)benzo[d]oxazole-2-carbaldehyde (CAS 1806283-78-2)
- 2-(Difluoromethyl)benzo[d]oxazole-7-carboxaldehyde (CAS 1806340-41-9)
- 2-(Difluoromethyl)benzo[d]oxazole-6-carboxaldehyde (CAS 1806396-07-5)
- 3-(Difluoromethyl)-5,5-difluoro-4,5,6,6a-tetrahydro-3aH-cyclopenta[d]isoxazole (CAS 1823381-24-3)
Recommended Standards
- 2-(Trifluoromethyl)thiazole-5-carboxylic Acid (CAS 1286734-84-6)
- 2-(3-Hydroxy-5-nitrophenyl)acetic acid (CAS 1261746-17-1)
- Methyl 2-hydroxy-6-nitrobenzoate (CAS 1261504-50-0)
- 3-(3,4-Difluorophenyl)-5-hydroxyisoxazole (CAS 1354937-46-4)
- 2-(2,5-Dihydrothiophen-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2489456-32-6)
- 4-chloro-1h-pyrazolo[3,4-b]pyridine-3-carbonitrile (CAS 1936189-92-2)
- 3-Iodocyclopent-2-en-1-one (CAS 61765-46-6)
- N-(9-Chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)-2-phenylacetamide (CAS 183721-15-5)
- 5-Bromo-3-fluoro-2-methylbenzaldehyde (CAS 1807174-24-8)
- 4-((2-(2-Oxo-2-(phenylamino)acetyl)hydrazono)methyl)phenyl 4-methoxybenzoate (CAS 880067-76-5)
- 4-Butoxy-2,3-difluoro-4'-((1s,4r)-4-propylcyclohexyl)-1,1'-biphenyl (CAS 323178-03-6)
- Naphthalene-2,3-dicarboxaldehyde (CAS 70848-82-7)
- (E)-4-oxo-4H-chromene-3-carbaldehyde oxime (CAS 130306-62-6)
- Insulin Degludec Impurity 8 (CAS CATO-C4X-21578)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com