N-(2-chloro-4-cyano-6-iodopyridin-3-yl)pivalamide CAS 1346446-97-6

Purity 97%+In StockPharmaceutical Standards
CAS No.1346446-97-6
Molecular FormulaC11H11ClIN3O
Molecular Weight363.58 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(2-chloro-4-cyano-6-iodopyridin-3-yl)pivalamide CAS 1346446-97-6 chemical structure

Description

The molecular framework of N-(2-chloro-4-cyano-6-iodopyridin-3-yl)pivalamide (C11H11ClIN3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

CATO supplies N-(2-chloro-4-cyano-6-iodopyridin-3-yl)pivalamide (CAS 1346446-97-6), a certified reference material (molecular formula C11H11ClIN3O, MW 363.58 g/mol) for analytical method development and quality control.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H11ClIN3O
Molecular Weight363.58 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentCl/I-containing
Nitrogen Atoms3

Related N Standards

Recommended Standards

Why CATO?