4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2,6-dinitrophenol CAS 1400872-33-4
| CAS No. | 1400872-33-4 |
| Molecular Formula | C12H5ClF3N3O5 |
| Molecular Weight | 363.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2,6-dinitrophenol is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2,6-dinitrophenol (CAS 1400872-33-4), molecular formula C12H5ClF3N3O5 and molecular weight 363.63 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C12H5ClF3N3O5, 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2,6-dinitrophenol contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 363.63 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2,6-dinitrophenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H5ClF3N3O5 |
| Molecular Weight | 363.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 5-Chloro-1-(tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazolo[3,4-b]pyridine (CAS 2888535-14-4)
- 4-((6-Chloro-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy)-3,5-difluoroaniline (CAS 1203656-90-9)
- N-(2-chloro-4-cyano-6-iodopyridin-3-yl)pivalamide (CAS 1346446-97-6)
- 6-Chloro-3-iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazolo[3,4-b]pyridine (CAS 1416714-43-6)
- 6-Chloro-3-iodo-1-tetrahydropyran-2-yl-pyrazolo[4,3-c]pyridine (CAS 1416714-59-4)
- 2-CHLORO-N-ETHYL-N-(4-(1,1,1,3,3,3-HEXAFLUORO-2-HYDROXYPROPAN-2-YL)PHENYL)ACETAMIDE (CAS 1951441-88-5)
- 5-Chloro-4-iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazolo[3,4-b]pyridine (CAS 2139360-13-5)
- N-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-3-(hydrazinecarbonyl)-5-methylisoxazole-4-carboxamide (CAS 338397-37-8)
Recommended Standards
- Macitentan Impurity 45 (CAS CATO-C4X-117545)
- 2,4,6-Trichlorophenyl (E)-2-phenylethene-1-sulfonate (CAS 1322270-45-0)
- Y97FBL93VW 74515-25-6 Laurdan 1-Dodecanone, 1-(6-(dimethylamino)-2-naphthalenyl)- 6-Dodecanoyl-2-dimethylaminonaphthalene 1-(6-(Dimethylamino)-2-naphthalenyl)-1-dodecanone UNII-Y97FBL93VW (CAS 74515-25-6)
- 6-Bromo-7-chloro-3-(3,5-dimethylphenyl)cinnolin-4-ol (CAS 1352723-57-9)
- methyl 8-chloroimidazo[1,2-a]pyrazine-2-carboxylate (CAS 1206981-34-1)
- 338393-13-8 5-[(4-Methylphenyl)methanesulfonyl]-1H-1,2,4-triazole DTXSID40366374 (CAS 338393-13-8)
- 2,6-Di(2H-1,2,3-triazol-4-yl)pyridine (CAS 1542234-40-1)
- 2,2-Dimethyl-1-(2,2,2-trifluoroethyl)piperazine (CAS 1267349-95-0)
- 2-Bromo-5-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1227268-83-8)
- 1,3,5-Trimethyl-6-morpholinopyrimidine-2,4(1H,3H)-dione (CAS 91194-40-0)
- Methyl (2Z)-2-(4-chlorobenzenesulfonyl)-3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]prop-2-enoate (CAS 1327187-59-6)
- 391873-67-9 Ethyl 4-acetyl-6-chloro-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate MFCD15732148 (CAS 391873-67-9)
- 1-{[3-Chloro-4-(trifluoromethoxy)phenyl]methyl}piperazine (CAS 1240565-36-9)
- Steroidogenesis-Activator Polypeptide (rat) (H-8855.0500) (CAS 108563-23-1)
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