2-Chloro-9-[2-deoxy-2-fluoro-5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-B-D-arabinofuranosyl]-9H-purin-6-amine CAS 134646-41-6
| CAS No. | 134646-41-6 |
| Molecular Formula | C10H14ClFN5O12P3 |
| Molecular Weight | 543.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carbohydrate-derived structure, an amide group, a phosphate ester group, fluorine/chlorine substitution, 2-Chloro-9-[2-deoxy-2-fluoro-5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-B-D-arabinofuranosyl]-9H-purin-6-amine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 543.62 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
2-Chloro-9-[2-deoxy-2-fluoro-5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-B-D-arabinofuranosyl]-9H-purin-6-amine (CAS 134646-41-6) is a high-purity analytical reference standard with the molecular formula C10H14ClFN5O12P3 and a molecular weight of 543.62 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H14ClFN5O12P3 |
| Molecular Weight | 543.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
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Recommended Standards
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- Relugolix Impurity 31 (CAS CATO-C4X-242931)
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- 2,3-Dihydrobenzofuran-4-carbaldehyde (CAS 209256-42-8)
- 5-Methyl-7,8-dihydro-1,6-naphthyridine (CAS 1176413-88-9)
- 3-Bromo-2-((1-(phenylsulfonyl)piperidin-4-yl)oxy)pyridine (CAS 1448052-53-6)
- 2-Chloro-3-((trimethylsilyl)ethynyl)pyridin-4-amine (CAS 1138444-10-6)
- 2,3,4,9-Tetrahydro-1H-carbazole-1-carboxylic acid (CAS 42497-46-1)
- Boron, [λ-(3,5-dimethyl-2H-pyrrol-2-ylidene-κN)-N-[(1S,2R)-2-hydroxy-1-(hydroxymethyl)heptadecyl]-3,5-dimethyl-1H-pyrrole-2-dodecanamidato-κN1]difluoro-, (T-4)- (CAS 1246355-59-8)
- 4-(glycolloylamino)phenylarsonicacid (CAS 144-87-6)
- [1,3]thiazolo[5,4-b]pyridin-2-ylhydrazine (CAS 57135-11-2)
- N-(4-(pyrrolidin-1-yl)phenyl)-3-(trifluoromethyl)benzamide (CAS 251097-28-6)
- D-Thr7-Tirzepatide (CAS CATO-CPTD788924)
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