4-Chloro-3-(methylsulfonyl)pyridine CAS 1346535-76-9
| CAS No. | 1346535-76-9 |
| Molecular Formula | C6H6ClNO2S |
| Molecular Weight | 191.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-3-(methylsulfonyl)pyridine.
4-Chloro-3-(methylsulfonyl)pyridine (CAS 1346535-76-9) is a high-purity analytical reference standard with the molecular formula C6H6ClNO2S and a molecular weight of 191.64 g/mol.
The molecular framework of 4-Chloro-3-(methylsulfonyl)pyridine (C6H6ClNO2S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Chloro-3-(methylsulfonyl)pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H6ClNO2S |
| Molecular Weight | 191.64 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 5-Chloro-2-(methylsulfonyl)pyridine (CAS 100560-78-9)
- 2-Chloro-N-(1,3,4-thiadiazol-2-yl)propanamide (CAS 1019456-17-7)
- 5-Chloro-2-(1,3-dioxolan-2-yl)-1,3-thiazole (CAS 1080061-38-6)
- 2-Chloro-5-ethyl-1,3-thiazole-4-carboxylic acid (CAS 1194374-29-2)
- 2-Chloro-4-ethylthiazole-5-carboxylic acid (CAS 1194374-35-0)
- Methyl 2-chloro-5-methylthiazole-4-carboxylate (CAS 1378819-18-1)
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Recommended Standards
- Pyridin-4-ylmethanesulfonyl chloride (CAS 130820-88-1)
- 2-Aminobenzenesulfonyl chloride (CAS 109061-25-8)
- Methyl 2-(4-chloro-1,3-thiazol-2-yl)acetate (CAS 1392804-93-1)
- 4-chloro-2-(1,3-dioxolan-2-yl)-1,3-thiazole (CAS 1423025-41-5)
- 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazin-2(1H)-one (CAS 2223053-64-1)
- 8-(Trifluoromethyl)quinolin-4(1H)-one (CAS 93919-57-4)
- 2-Methyl-5-[(4-methylpiperazin-1-yl)sulfonyl]benzoic acid (CAS 1040343-07-4)
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- N-n-Butyl-N-methylethanolamine (CAS 2893-48-3)
- 5,6-Bis(4-methoxyphenyl)pyridazine-3-carbonitrile (CAS 375793-04-7)
- 2-(Trifluoromethyl)quinoline-6-carboxylic acid (CAS 952182-51-3)
- 5-((3-Chlorophenoxy)methyl)furan-2-carbohydrazide (CAS 827588-48-7)
- Calcium arsenate (CAS 7778-44-1)
- Peptide 6A (H-6905.0005) (CAS 73549-32-3)
Why CATO?
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