2-Hydroxy Irinotecan CAS 1346597-39-4
| CAS No. | 1346597-39-4 |
| Molecular Formula | C33H38N4O7 |
| Molecular Weight | 602.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Hydroxy Irinotecan is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-Hydroxy Irinotecan (CAS 1346597-39-4), a certified reference material (molecular formula C33H38N4O7, MW 602.68 g/mol) for analytical method development and quality control.
2-Hydroxy Irinotecan (C33H38N4O7) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C33H38N4O7 |
| Molecular Weight | 602.68 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 4 |
Related Hydroxy Standards
- 2,2'-[4-Hydroxy-4-oxidodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-2,6-diyl]bis[quinoline] (CAS 1429427-21-3)
- 2,2'-[(11bS)-4-Hydroxy-4-oxidodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-2,6-diyl]bis[quinoline] (CAS 1502024-23-8)
- 21(S)-Hydroxy Montelukast (CAS 184763-29-9)
- (11bS)-4-Hydroxy-2,6-di(1-naphthyl)dinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepine 4-Oxide (CAS 929097-93-8)
- (11bS)-4-Hydroxy-2,6-di-2-naphthalenyl-4-oxide-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin (CAS 874948-60-4)
- 8'-Hydroxy Dihydroergotamine (CAS 90650-44-5)
- (R)-4-Hydroxy-2,6-bis(4-nitrophenyl)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine 4-sulfide (CAS 1706459-42-8)
- 4-Hydroxy-2,6-bis(4-nitrophenyl)-8,9,10,11,12,13,14,15-octahydrodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine 4-oxide (CAS 2129645-31-2)
Recommended Standards
- Irinotecan EP Impurity M (CAS 185336-12-3)
- Irinotecan Impurity 63 (CAS CATO-C4X-166763)
- Ceftazidime Impurity 92 (CAS CATO-C4X-121292)
- Mavacamten Impurity 18 (CAS CATO-C4X-298218)
- (2,4-Dimethoxyphenyl)(pyridin-2-yl)methanol (CAS 1426434-79-8)
- tert-butyl N-{2-bromo-[1,2,4]triazolo[1,5-a]pyridin-7-yl}carbamate (CAS 1380331-50-9)
- (3-(4-Chlorophenyl)-5,6-dihydropyridazin-1(4H)-yl)(3-methoxyphenyl)methanone (CAS 339100-13-9)
- (S)-Benzyl 3-(tosyloxy)piperidine-1-carboxylate (CAS 1354020-77-1)
- (S)-2-Amino-N-methyl-N-(pyrazin-2-ylmethyl)propanamide (CAS 1354020-61-3)
- 1-(6-(4-Amino-3-methoxyphenyl)-2,6-diazaspiro[3.3]Heptan-2-yl)ethan-1-one (CAS 1637470-12-2)
- 3-Fluoro-2-methyl-4-nitropyridine (CAS 1780090-68-7)
- 6-Bromo-1H-indol-2-amine hydrochloride (CAS 28493-03-0)
- 2-Chloro-6-[(piperidin-1-yl)carbonyl]pyridine (CAS 720693-20-9)
- (Gly1,Ser3·22,Gln?·3?,Thr?,Arg1?,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human) (CAS 313988-89-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com