Mavacamten Impurity 18 CAS CATO-C4X-298218
| CAS No. | CATO-C4X-298218 |
| Molecular Formula | C32H38N6O6 |
| Molecular Weight | 602.68 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Mavacamten Impurity 18.
Mavacamten Impurity 18 (CAS CATO-C4X-298218) is a certified pharmaceutical impurity reference standard with the molecular formula C32H38N6O6 and a molecular weight of 602.68 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Mavacamten Impurity 18 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 602.68 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C32H38N6O6 |
| Molecular Weight | 602.68 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Mavacamten Standards
- Mavacamten Impurity 20 (CAS CATO-C4X-298220)
- Mavacamten Impurity 13 (CAS 1642289-38-0)
- Mavacamten Impurity 14 (CAS CATO-C4X-298214)
- Mavacamten Impurity 12 (CAS CATO-C4X-298212)
- Mavacamten Impurity 16 (CAS CATO-C4X-298216)
- Mavacamten Impurity 11 (CAS 1642289-43-7)
- Mavacamten Impurity 19 (CAS CATO-C4X-298219)
- Mavacamten-D5 (CAS 2453251-00-6)
Recommended Standards
- Irinotecan Impurity 63 (CAS CATO-C4X-166763)
- Gadolinium(III) sulfate (CAS 13628-54-1)
- 2-Hydroxy Irinotecan (CAS 1346597-39-4)
- Ibrutinib Impurity 23 (CAS CATO-C4X-106423)
- Azilsartan Impurity 37 (CAS 80841-79-8)
- Ziprasidone Impurity 30 (CAS 188797-80-0)
- Quetiapine impurity 74 (CAS 99153-65-8)
- N-(Aminomethyl)benzamide (CAS 67908-02-5)
- 5-Iodo-1-propyl-1H-pyrazole (CAS 1823431-57-7)
- 5-Bromo-6-methyl-1-{[2-(trifluoromethyl)phenyl]methyl}-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 2102411-35-6)
- 2,5-Difluoro-4-iodopyridine (CAS 1017793-20-2)
- 1-Tosyl-1,5,6,7-tetrahydro-4H-indol-4-one (CAS 35577-89-0)
- 4-Chloro-1-(3,3,3-trifluoropropyl)-1h-pyrazol-3-amine (CAS 1343188-88-4)
- Semaglutide impurity 32 (CAS CATO-C4X-222632)
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