Esomeprazole Impurity 74 CAS 1346599-74-3
| CAS No. | 1346599-74-3 |
| Molecular Formula | C26H30N4O5S |
| Molecular Weight | 510.61 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Esomeprazole Impurity 74 (CAS 1346599-74-3) is a certified pharmaceutical impurity reference standard with the molecular formula C26H30N4O5S and a molecular weight of 510.61 g/mol.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Esomeprazole Impurity 74 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 510.61 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C26H30N4O5S |
| Molecular Weight | 510.61 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Esomeprazole Standards
- Esomeprazole Impurity 12 (CAS 1803449-02-6)
- Esomeprazole Impurity 130 (CAS CATO-C4X-1112130)
- Esomeprazole Impurity 23 (CAS 1422063-97-5)
- Esomeprazole impurity 137 (CAS CATO-C4X-1112137)
- Esomeprazole Impurity 71 (CAS 1076199-93-3)
- Esomeprazole impurity 139 (CAS CATO-C4X-1112139)
- Esomeprazole impurity 141 (CAS CATO-C4X-1112141)
- Esomeprazole Impurity 131 (CAS CATO-C4X-1112131)
Recommended Standards
- 3,5-Di-tert-butyl-N-(6-(dimethylamino)-1-(4-fluorophenyl)-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-4-hydroxybenzamide (CAS 595558-89-7)
- Cefepime Impurity 14 (CAS CATO-C4X-119314)
- Budesonide 21-Sulfate (CAS 1436796-04-1)
- Dodecyl α-D-maltopyranoside (CAS 116183-64-3)
- Chlorhexidine Impurity 35 (CAS 2734290-31-2)
- Fluoxetine Impurity 35 (CAS 21970-65-0)
- Tirofiban Impurity 65 DiHCl (CAS CATO-C4X-125465)
- Cefazolin Impurity 26 (CAS CATO-C4X-157726)
- (4-Aminophenyl)(4-(methylamino)phenyl)methanone (CAS 81260-56-2)
- 3-methyl-5-(piperazin-1-ylmethyl)-1,2-oxazole (CAS 173850-53-8)
- 1,3-bis(2,6-diisopropylphenyl)-2H-imidazole;3-chloropyridine;dichloropalladium 927706-57-8 {1,3-bis[2,6-bis(propan-2-yl)phenyl]imidazolidin-2-yl}dichloro(3-chloro-1|E?-pyridin-1-yl)palladium (CAS 927706-57-8)
- 2-Chloro-4,6-dimethoxybenzo[d]thiazole (CAS 1023559-29-6)
- (3-Methoxy-5-(trifluoromethyl)pyridin-2-yl)methanamine (CAS 1256811-10-5)
- Smac-N7 Peptide (CAS 401913-57-3)
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