Tolvaptan Impurity 7 CAS 1346599-75-4
| CAS No. | 1346599-75-4 |
| Molecular Formula | C26H25ClN2O5 |
| Molecular Weight | 480.94 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 480.94 g/mol gives Tolvaptan Impurity 7 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Tolvaptan Impurity 7 (CAS 1346599-75-4) is a certified pharmaceutical impurity reference standard with the molecular formula C26H25ClN2O5 and a molecular weight of 480.94 g/mol.
Structurally, Tolvaptan Impurity 7 (C26H25ClN2O5) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 480.94 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Tolvaptan Impurity 7 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H25ClN2O5 |
| Molecular Weight | 480.94 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Tolvaptan Standards
- Tolvaptan Impurity 15 (CAS 1346599-56-1)
- Tolvaptan Impurity 25 (CAS 2921676-63-1)
- Tolvaptan impurity 112 (CAS CATO-C4X-1955112)
- Tolvaptan Impurity 48 (CAS CATO-C4X-195548)
- Tolvaptan Impurity 51 (CAS CATO-C4X-195551)
- Tolvaptan Impurity 96 (CAS 1587638-01-4)
- Tolvaptan Impurity 65 (CAS CATO-C4X-195565)
- Tolvaptan Impurity 47 (CAS 150683-52-6)
Recommended Standards
- Empagliflozin Impurity 48 (CAS 915095-96-4)
- Bexagliflozin Impurity 8 (CAS CATO-C4X-33228)
- Empagliflozin Impurity 313 (CAS 1620758-25-9)
- 1-Bromoperfluoro(4-methyl-3,6-dioxaoctane) (CAS 1482416-44-3)
- Tiotropium EP Impurity A (CAS 4746-63-8)
- Lasmiditan Impurity 15 HCl (CAS CATO-C4X-247815)
- Rosuvastatin Impurity 88 (CAS CATO-C4X-116988)
- 2-butyl-5-methyl-2,4-dihydro-3H-pyrazol-3-one (CAS 65156-70-9)
- 2-Amino-4-methyl-5-phenylthiazole (CAS 28241-62-5)
- n-(1-Methoxybutan-2-yl)pyridin-2-amine (CAS 1481399-20-5)
- 2-Amino-N-isopropyl-N-((1-methylpyrrolidin-3-yl)methyl)acetamide (CAS 1353960-15-2)
- 3-(P-tolyl)prop-2-yn-1-amine (CAS 16017-26-8)
- 4-(2-(4-Fluorophenyl)hydrazono)-2,3-dihydro-4H-thieno[2,3-b]thiopyran 1,1-dioxide (CAS 478043-36-6)
- Neuroendocrine Regulatory Peptide-4 (human, mouse, rat) (H-7266.1000) (CAS 922704-18-5)
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