Penbutolol-d9-HCl CAS 1346605-01-3
| CAS No. | 1346605-01-3 |
| Molecular Formula | - |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Penbutolol-d9-HCl.
Penbutolol-d9-HCl (CAS 1346605-01-3) is a high-purity analytical reference standard with the molecular formula C18H20D9NO2HCl and a molecular weight of 336.95 g/mol.
Owing to deuterium isotope labeling, a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Penbutolol-d9-HCl is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 336.95 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H20D9NO2 HCl |
| Molecular Weight | 336.95 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Penbutolol Standards
- Penbutolol EP Impurity A (CAS 112160-87-9)
- Penbutolol EP Impurity A Racemate (CAS 121010-10-4)
- Penbutolol Hydrochloride (CAS 28163-36-2)
- Penbutolol Impurity 13 (CAS 32396-10-4)
- rac Penbutolol (CAS 36507-48-9)
- (S)-Penbutolol Sulfate (CAS 38363-32-5)
- Penbutolol (CAS 38363-40-5)
- (R)-Penbutolol (CAS 38363-41-6)
Recommended Standards
- (S)-2-((tert-Butoxycarbonyl)amino)-3-(3,5-dibromo-4-hydroxyphenyl)propanoic acid (CAS 58960-71-7)
- 2-Amino-N-(4-(diethylamino)-2-methylphenyl)benzamide (CAS 16231-75-7)
- 2-Chloro-4-fluorocinnamic acid (CAS 133220-86-7)
- 3-Amino-6-bromo-8-methylquinazolin-4(3H)-one (CAS 1092345-74-8)
- 3-Fluoro-3,5,6-trimethylindolin-2-one (CAS 1398504-26-1)
- 5-(Cyclohexylmethyl)isoxazol-3-amine (CAS 1484341-97-0)
- 2-((((9H-fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-4,4-dimethylpentanoic acid (CAS 1699606-82-0)
- (R)-1,3-Butanediol, 2,3-dimethyl (CAS 73295-16-6)
- (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-((2-(thiazol-2-yl)ethyl)amino)-9H-purin-9-yl)tetrahydrofuran-3,4-diol (CAS 143354-83-0)
- Tirzepatide Impurity 9 (CAS CATO-C4X-32409)
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