(E)-3-(4-hydroxyphenyl)-N-[2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl]prop-2-enamide CAS 1346606-33-4
| CAS No. | 1346606-33-4 |
| Molecular Formula | C23H28N2O2 |
| Molecular Weight | 364.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
(E)-3-(4-hydroxyphenyl)-N-[2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl]prop-2-enamide (CAS 1346606-33-4) is a high-purity analytical reference standard with the molecular formula C23H28N2O2 and a molecular weight of 364.48 g/mol.
The molecular framework of (E)-3-(4-hydroxyphenyl)-N-[2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl]prop-2-enamide (C23H28N2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H28N2O2 |
| Molecular Weight | 364.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
Related E Standards
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Recommended Standards
- Pentanoic acid, 3-methyl-, (3aR,4S,7aR)-2,3,3a,4,7,7a-hexahydro-5-[(1S)-4-hydroxy-1-methylbutyl]-6-methyl-3-methylene-2-oxo-4-benzofuranyl ester (CAS 1260151-66-3)
- Tetrahydro Aldosterone (CAS 13489-75-3)
- Methyl 2-hydroxy-6-(2-(1,2,3,4,4a,9,9a,10-octahydroanthracen-9-yl)ethyl)benzoate (CAS 1217661-95-4)
- tert-Butyl 4-(((6-(diethylamino)pyrimidin-4-yl)oxy)methyl)piperidine-1-carboxylate (CAS 1353947-42-8)
- 3'-Cyano-2'-fluoro-[1,1'-biphenyl]-4-carboxylic acid (CAS 1261998-23-5)
- 4,6-Dimethyl-2-piperazin-1-yl-1,3-benzothiazole (CAS 1105194-44-2)
- (1S,4aR,5S,8aR)-5-((R)-3-Hydroxy-3-methylpent-4-en-1-yl)-1,4a-dimethyl-6-methylenedecahydronaphthalene-1-carboxylic acid (CAS 1909-90-6)
- 2-Fluoro-6-(methylthio)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 2137928-55-1)
- 6-ACetamido-2-acetylpyridine (CAS 127682-72-8)
- 3-((1-Cyclopropylethyl)amino)tetrahydrothiophene 1,1-dioxide (CAS 1019559-80-8)
- 3-(4-sec-Butyl-phenyl)-2-mercapto-3H-quinazolin-4-one (CAS 554442-51-2)
- 1-(2-Amino-3-chloro-6-fluorophenyl)naphthalen-2-ol (CAS 1424386-52-6)
- 2-(3-isopropoxyphenyl)ethanamine (CAS 149489-17-8)
- Semaglutide impurity 215 (CAS CATO-C4X-2226215)
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