3,3-Bis(4-hydroxyphenyl)benzo[de]isochromen-1(3H)-one CAS 5627-39-4
| CAS No. | 5627-39-4 |
| Molecular Formula | C24H16O4 |
| Molecular Weight | 368.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3,3-Bis(4-hydroxyphenyl)benzo[de]isochromen-1(3H)-one is closely related to a flavonoid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 3,3-Bis(4-hydroxyphenyl)benzo[de]isochromen-1(3H)-one (CAS 5627-39-4), a certified reference material (molecular formula C24H16O4, MW 368.38 g/mol) for analytical method development and quality control.
3,3-Bis(4-hydroxyphenyl)benzo[de]isochromen-1(3H)-one (C24H16O4) contains a flavonoid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H16O4 |
| Molecular Weight | 368.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Bis Standards
- 3-(4-Hydroxyphenyl)-2-[4-(trifluoromethoxy)benzoylamino]propanoic acid (CAS 1008918-81-7)
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- 3-((4-Hydroxyphenyl)(thiophen-2-ylmethyl)amino)benzo[d]isothiazole 1,1-dioxide (CAS 443319-38-8)
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Recommended Standards
- 3-(4-Fluorophenyl)-6-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidin-7-amine (CAS 685107-30-6)
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- 2-Amino-4-[3-methoxy-4-(propan-2-yloxy)phenyl]-7-methyl-5-oxo-4H,5H-pyrano[3,2-c]pyran-3-carbonitrile (CAS 625375-34-0)
- 4,4'-(Naphthalene-1,4-diyl)dibenzoic acid (CAS 2305793-87-5)
- (6-Bromo-3-methoxypyrazin-2-yl)methanol (CAS 2639836-45-4)
- (1s)-1-(3-Fluoropyridin-2-yl)ethan-1-amine hydrochloride (CAS 1311254-90-6)
- Benzyl (3S,4S)-4-amino-3-fluoropiperidine-1-carboxylate (CAS 1523530-09-7)
- 1-(4-(2-(6-Amino-9H-purin-9-yl)ethoxy)phenyl)ethan-1-one (CAS 432016-77-8)
- Ropivacaine EP Impurity G HCI (CAS 112773-90-7)
- 2-(6-Bromo-3-(trifluoromethyl)pyridin-2-yl)acetic acid (CAS 1805029-89-3)
- N-(3,5-Dichlorobenzyl)-4-methoxyaniline (CAS 1040688-21-8)
- 4-Bromo-3-(difluoromethyl)-2-fluoro-6-hydroxypyridine (CAS 1806903-11-6)
- 5,8-diazaspiro[3.5]nonan-6-one (CAS 1419209-31-6)
- Insulin Glulisine (CAS 207748-29-6)
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