(S)-Amlodipine-d4 CAS 1346617-19-3
| CAS No. | 1346617-19-3 |
| Molecular Formula | - |
| Molecular Weight | 412.90 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (S)-Amlodipine-d4 is closely related to deuterium isotope labeling, a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(S)-Amlodipine-d4 (CAS 1346617-19-3), molecular formula C20H21D4ClN2O5 and molecular weight 412.90 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C20H21D4ClN2O5, (S)-Amlodipine-d4 contains deuterium isotope labeling, a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 412.90 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (S)-Amlodipine-d4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H21D4ClN2O5 |
| Molecular Weight | 412.90 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related S Standards
- Amlodipine-d4 (CAS 1185246-14-3)
- (R)-Amlodipine-d4 (CAS 1346616-97-4)
- Amlodipine Impurity 150 (CAS CATO-C4X-1095150)
- Amlodipine (S)-Isomer (CAS 103129-82-4)
- Amlodipine (CAS 88150-42-9)
- (R)-Amlodipine (CAS 103129-81-3)
- Amlodipine para-Chloro Impurity (CAS 90445-02-6)
- Amlodipine Metabolite 5 (CAS 114018-75-6)
Recommended Standards
- 4-[(4-Chlorophenyl)sulfanyl]-N-(2,3-dimethylphenyl)-3-nitrobenzamide (CAS 303988-22-9)
- 4-[(1E)-3-(4-Methylphenyl)-3-oxoprop-1-en-1-yl]phenyl 4-chlorobenzene-1-sulfonate (CAS 331460-92-5)
- 2,2-Dibromo-1-(5-(2,4-dichlorophenyl)furan-2-yl)ethan-1-one (CAS 338756-44-8)
- 7-(Benzyloxy)-2-chloro-6-methoxy-N-(1-methylpiperidin-4-yl)quinazolin-4-amine (CAS 1197196-50-1)
- 3-(Dimethylamino)-3H,4H-thieno[3,2-d]pyrimidin-4-one (CAS 338750-84-8)
- 1-Morpholino-1-cyclododecene (CAS 101471-80-1)
- Methyl 3,3-dimethyl-2-{[2-nitro-4-(trifluoromethyl)phenyl]amino}butanoate (CAS 1214793-21-1)
- Hesperidin Impurity 10 (CAS CATO-C4X-332710)
- 1-Bromo-2-methylpropan-2-amine (CAS 99187-35-6)
- 6-(3-Methylbenzyl)isothiazolo[4,3-d]pyrimidine-5,7(4H,6H)-dione (CAS 1326932-82-4)
- 2-((4-(4-Methoxyphenyl)pyrimidin-2-yl)thio)acetonitrile (CAS 392718-85-3)
- 3-iodo-1-methyl-indazole-5-carbonitrile (CAS 1426423-63-3)
- 4-Ethyl-3-((4-fluorobenzyl)thio)-5-(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)-4H-1,2,4-triazole (CAS 956741-90-5)
- Semaglutide impurity 64 (CAS CATO-C4X-222664)
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