Amlodipine para-Chloro Impurity CAS 90445-02-6
| CAS No. | 90445-02-6 |
| Molecular Formula | C20H25ClN2O5 |
| Molecular Weight | 408.88 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Amlodipine para-Chloro Impurity.
CATO supplies Amlodipine para-Chloro Impurity (CAS 90445-02-6), a pharmacopoeial impurity reference standard (molecular formula C20H25ClN2O5, MW 408.88 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Amlodipine para-Chloro Impurity is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 408.88 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Amlodipine para-Chloro Impurity under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H25ClN2O5 |
| Molecular Weight | 408.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Amlodipine Standards
- Amlodipine (S)-Isomer (CAS 103129-82-4)
- Amlodipine (CAS 88150-42-9)
- (R)-Amlodipine (CAS 103129-81-3)
- Amlodipine Impurity 150 (CAS CATO-C4X-1095150)
- Amlodipine Metabolite 5 (CAS 114018-75-6)
- Amlodipine Besylate EP Impurity D (CAS 113994-41-5)
- (S)-Amlodipine-d4 (CAS 1346617-19-3)
- Amlodipine-d4 (CAS 1185246-14-3)
Recommended Standards
- 4-((Tribromomethyl)sulfonyl)phenol (CAS 1224635-68-0)
- 21-Dehydro Clocortolone (CAS 61744-29-4)
- Clobetasone Butyrate EP Impurity A (CAS 54063-32-0)
- N-(1-(tert-butyl)-3-(4-chlorophenyl)-4-cyano-1H-pyrazol-5-yl)-4-methoxybenzamide (CAS 956784-40-0)
- Pazufloxacin Impurity 17 (CAS 164851-44-9)
- Linaprazan Impurity 3 (CAS CATO-C4X-34863)
- Imatinib EP Impurity B (CAS 581076-65-5)
- 2-Cyclopropoxy-5-ethylbenzonitrile (CAS 1243443-10-8)
- 5-Hydroxy-2-(methylsulfonamido)benzamide (CAS 1243381-21-6)
- 2-azabicyclo[2.1.1]hexane-2-sulfonyl chloride (CAS 2225142-06-1)
- tert-Butyl 3-(4-hydroxyphenyl)piperazine-1-carboxylate (CAS 889956-81-4)
- 5-Bromo-4-hydroxypicolinonitrile (CAS 1369850-06-5)
- 5-Benzyloxy-2-methylbenzoic acid ethyl ester (CAS 2221812-01-5)
- (2S)-2-amino-4-(hydroxymethylphosphinyl)butanoyl-L-alanyl-L-alanine (2S)-2-amino-4-[hydroxy(methyl)phosphinoyl]butyryl-L-alanyl-L-alanine 2-Amino-4-(methylphosphino)butyrylalanylalanine 35597-43-4 Antibiotic SF 1293 Bialaphos CHEBI:3088 L-phosphinothricyl-L-alanyl-L-alanine N-{(2S)-2-amino-4-[hydroxy(methyl)phosphoryl]butanoyl}-L-alanyl-L-alanine PTT Phosphinothricylalanylalanine bilanafos gamma-(Hydroxymethylphosphinyl)-L-alpha-aminobutyryl-L-alanyl-L-alanine phosphinothricin tripeptide (CAS 35597-43-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com