(5-(3-Chloro-5-fluorophenyl)pyridin-3-yl)methanamine CAS 1346692-21-4

Description

The occurrence of (5-(3-Chloro-5-fluorophenyl)pyridin-3-yl)methanamine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(5-(3-Chloro-5-fluorophenyl)pyridin-3-yl)methanamine (CAS 1346692-21-4), molecular formula C12H10ClFN2 and molecular weight 236.67 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution, (5-(3-Chloro-5-fluorophenyl)pyridin-3-yl)methanamine is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 236.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (5-(3-Chloro-5-fluorophenyl)pyridin-3-yl)methanamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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