Ioversol Impurity 8 CAS 134768-83-5
| CAS No. | 134768-83-5 |
| Molecular Formula | C13H14I3N3O6 |
| Molecular Weight | 688.98 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ioversol Impurity 8.
Ioversol Impurity 8 (CAS 134768-83-5) is a certified pharmaceutical impurity reference standard with the molecular formula C13H14I3N3O6 and a molecular weight of 688.98 g/mol.
The molecular framework of Ioversol Impurity 8 (C13H14I3N3O6) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ioversol Impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H14I3N3O6 |
| Molecular Weight | 688.98 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 3 |
Related Ioversol Standards
- Ioversol impurity 30 (CAS CATO-C4X-209130)
- Ioversol impurity 32 (CAS CATO-C4X-209132)
- Ioversol Impurity 24 (CAS CATO-C4X-209124)
- Ioversol Impurity 7 (CAS CATO-C4X-20917)
- Ioversol Impurity 1 (CAS 134768-85-7)
- Ioversol impurity 34 (CAS CATO-C4X-209134)
- Ioversol Impurity 20 (CAS CATO-C4X-166420)
- Ioversol Impurity 13 (CAS 2253945-67-2)
Recommended Standards
- Phorbol-12-Retinoate-13-Acetate (CAS 80188-99-4)
- Iobitridol Impurity 25 (CAS CATO-C4X-317825)
- Di-tert-butyl 2,2'-(4,10-bis(6-hydroxy-2,2-dimethyl-1,3-dioxepan-5-yl)-1,4,7,10-tetraazacyclododecane-1,7-diyl)diacetate (CAS 245486-50-4)
- Brain CPE (CAS 112130-78-6)
- Iomeprol Impurity 19 (CAS CATO-C4X-182019)
- Palbociclib Impurity 191 (CAS CATO-C4X-1125191)
- Finasteride Impurity 9 (CAS CATO-C4X-16459)
- Butyl 4-(2-mercapto-4,4-dimethylpyrimidin-1(4H)-yl)benzoate (CAS 1142213-28-2)
- Steviol 19-glucoside (CAS 64977-89-5)
- (E)-4-(pyrrolidin-1-yl)but-2-enoic acid (CAS 848185-03-5)
- 6-Bromo-2-iodo-1H-pyrrolo[3,2-b]pyridine (CAS 1260381-61-0)
- 1-(2,2-Difluoroethyl)piperidin-4-ol (CAS 1248029-58-4)
- 2-(Naphthalen-1-ylamino)thiazole-4-carboxylic acid (CAS 165682-87-1)
- Des-Pro36-Tirzepatide (CAS CATO-CPTD788937)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com