6-chloro-3-methoxy-pyrazin-2-amine CAS 13484-49-6
| CAS No. | 13484-49-6 |
| Molecular Formula | C5H12ClN3O |
| Molecular Weight | 165.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-chloro-3-methoxy-pyrazin-2-amine (CAS 13484-49-6), molecular formula C5H12ClN3O and molecular weight 165.62 g/mol, is a CATO reference standard with documented purity and traceability.
6-chloro-3-methoxy-pyrazin-2-amine (C5H12ClN3O) contains an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 6-chloro-3-methoxy-pyrazin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H12ClN3O |
| Molecular Weight | 165.62 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1960 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
- 5-Chloro-3,4-dihydroisoquinoline (CAS 1346177-17-0)
- 3-chloro-6-methoxypyrazin-2-amine (CAS 13484-56-5)
- 2-(4-chlorobut-1-yn-1-yl)pyridine (CAS 1339733-13-9)
- 1-(3-Chlorophenyl)prop-2-yn-1-amine (CAS 1420791-51-0)
- Methyl 2-(3-bromo-2,5-difluorophenyl)acetate (CAS 1805119-99-6)
- N1,N1,N2,N2-Tetramethyl-1,2-benzenediamine (CAS 704-01-8)
- 3-Benzoyl-2,5-dihydrofuran (CAS 119476-25-4)
- Ipecoside (CAS 15401-60-2)
- 2-[(6-Chloro-4-trifluoromethyl-pyridin-2-yl)-methyl-hydrazono]-propionic acid ethyl ester (CAS 1311283-76-7)
- n-Methyl-1-(5-methylisoxazol-4-yl)methanamine (CAS 1248913-16-7)
- Brexpiprazole Impurity 50 (CAS CATO-C4X-113150)
- 4-Amino-N-cyclohexyl-2-thioxo-3-(o-tolyl)-2,3-dihydrothiazole-5-carboxamide (CAS 946330-49-0)
- Avanafil Impurity 56 (CAS 2310299-29-5)
- Acetyl-Tau Peptide (273-284) amide trifluoroacetate salt (CAS 1684399-52-7)
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